Is your gut microbiome preventing weight loss? | Dr. Suzanne Devkota and Prof. Tim Spector

ZOE Science & Nutrition

Belly fat is more than just stubborn weight – it plays a complex role in our health, interacting with the immune system and gut bacteria. But could gut microbes hold the key to understanding and managing belly fat?

In this episode, Dr. Suzanne Devkota, Director of the Microbiome Research Institute at Cedars-Sinai, shares groundbreaking findings on how gut bacteria interact with belly fat. Tim Spector, professor of epidemiology and scientific co-founder at ZOE, also joins the conversation to explain how the diversity of your gut bacteria affects weight and overall health.

Together, our guests share surprising ways the microbiome influences fat storage and offer practical tips for supporting gut health.

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Timecodes

00:00 The risks of internal fat

01:45 Quickfire questions

03:12 What is belly fat?

04:30 How dangerous is internal fat?

05:44 How our body uses belly fat

16:20 Groundbreaking study on gut bacteria

21:05 These gut bacteria live in your fat tissue

24:50 Gut health and your immune system

31:58 Why microbes are essential to survive

38:30 Why gut health starts at birth

46:40 The importance of sampling your gut microbes

50:50 Two changes you can make right now

53:02 Easy fermented eating tips

55:10 Why not all pickles are fermented

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Free resources from ZOE

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks

Mentioned in today's episode

Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans (2020), published in Cell

Our extended microbiome: The human-relevant metabolites and biology of fermented foods (2024), published in Cell Metabolism

Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial (2024), published in Nature

Heritable components of the human fecal microbiome are associated with visceral fat (2016) published in Genome Biology

Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation (2019), published in Scientific Reports

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Episode transcripts are available here.