Tit Talk #3 - Breast Cancer & Vaginal Estrogen: Is Vaginal Estrogen Therapy Safe To Use?

Too Young For This Shit | AYA Breast Cancer Podcast

In the third episode of Tit Talk, Rosalina guides us through a study featured in JAMA Oncology in November 2023. Examining data from nearly 50,000 women in the UK, the study investigates the potential link between vaginal estrogen therapy and breast cancer-related mortality. The study's findings reveal no evidence of an elevated risk. As always, Rosalina encourages listeners to stay informed, seek advice from healthcare professionals, and feel empowered to make decisions that align with their well-being.

In this third season of the podcast, we had a dedicated episode on sexual health, where we spoke to medical oncologist and sexual health expert Dr. Laila Agrawal on a misconception about hormone-positive breast cancer and the use of vaginal estrogen. It's an episode worth catching up on, especially since discussions about women's sexual health are often overlooked.

Resources:

Main study: https://jamanetwork.com/journals/jamaoncology/article-abstract/2811413

Dr. Agrawal analysis of the main study: https://www.instagram.com/reel/C0HTzb2Ad9k/

More info on the model used in the study: https://sphweb.bumc.bu.edu/otlt/mph-modules/bs/bs704_survival/BS704_Survival6.html

ASCO 2018 recommendation: https://ascopubs.org/doi/full/10.1200/JCO.2017.75.8995

Medical study general analysis: https://www.youtube.com/watch?v=BHsdpg1OOf0

North American Menopause Society recommendation: https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf

Recurrence study: https://pubmed.ncbi.nlm.nih.gov/37535961/

Dr. Agrawal’s post re: recurrence study: https://www.instagram.com/p/C0P9wdsg1nf/