Episode #76 | Treating Type I Diabetes with FRESH Bioprinting: Interview with Mike Graffeo

The Lattice (Official 3DHEALS Podcast)

Discover FRESH 3D bioprinting with Mike Graffio, CEO and co-founder of Fluoform3D. Having met at Carnegie Mellon University, Mike and Adam Feinberg have been on a mission to revolutionize the field of bioprinting, focusing on creating replacement tissues and organs without introducing foreign substances into the body. Mike shares the captivating journey from their engineering days in the 1990s through a pivotal 2015 conversation that transformed their research into a thriving startup and onto achieving significant milestones like developing living cardiac tissues and heart valves by 2018.
Our conversation uncovers the next frontier in 3D bioprinting, particularly the promising strides in islet cell replacement therapy for diabetes. You'll hear about how the FRESH bioprinitng propels this innovative field forward. With breakthroughs in small animal models showing potential for diabetes management, we explore how the team is gearing up for more extensive studies and human clinical trials. This episode also delves into their strategic fundraising efforts and partnerships to bring these advancements to life.
Summary:
• Overview of Fluoform3D and its founding story
• Explanation of FRESH Technology and its significance in bioprinting
• Current progress in cardiac applications and in vitro tissues
• Ongoing projects related to therapeutic applications for type I diabetes
• Insights into navigating funding and building investor relationships
• Discussion on regulatory pathways and interactions with the FDA
• Emphasis on company culture and team dynamics
• Recommendations for industry insights and staying informed about bioprinting trends
Show Notes:
Instagram interview with Mike in 2021
Fluidform3D website
Breakthrough publication in 2019 made it to the cover of Science magazine-"FRESH 3D Printing Used to Rebuild Functional Components of the Human Heart"
YouTube Video: https://youtu.be/BJbReV0v7Co

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1. Episode #76 | Treating Type I Diabetes with FRESH Bioprinting: Interview with Mike Graffeo (00:00:00)

2. Fluidform3D Founding Journey (00:00:01)

3. FRESH 3D Bioprinting Technology Overview (00:13:21)

4. Building Effective Teams in Biotech (00:26:11)

5. Leadership, Bioprinting, and Stoicism (00:35:22)