E111: PEXIVAS Subsets with Mike Walsh & Mats Junek

The Evidence Based Rheumatology Podcast

At ACR23 I had a twitter-disagreement about steroid tapers from PEXIVAS with Mike Walsh, the lead author on the PEXIVAS trial. He kindly agreed to join me for a moderated discussion. Loved hearing his perspective and have to admit he pulled me closer to his practice... but not all the way there. Longer podcast than usual but I prefer to release audio uncut and this took as long as it needed! Hoping y'all enjoy.

Articles referenced during the podcast:

PEXIVAS: https://www.nejm.org/doi/full/10.1056/nejmoa1803537

PEXIVAS DAH Subset: https://www.atsjournals.org/doi/10.1164/rccm.202308-1426OC

Fussner Abstract: https://acrabstracts.org/abstract/characteristics-and-outcomes-of-participants-with-and-without-diffuse-alveolar-hemorrhage-in-the-plasma-exchange-and-glucocorticoids-in-severe-anca-associated-vasculitis-pexivas-trial/

Walsh Meta Analysis: https://pubmed.ncbi.nlm.nih.gov/35217545/