Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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المحتوى المقدم من TGen Talks. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرة بواسطة TGen Talks أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.
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Episode 43: The Genomics of Brain Tumors
Manage episode 307856760 series 1936276
المحتوى المقدم من TGen Talks. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرة بواسطة TGen Talks أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.
Genomic analysis of a cancer tumor is fairly common these days. Researchers sequence and compare a patient’s non-cancerous DNA with their tumor DNA to identify changes that may allow a patient to receive medicine that specifically targets those changes. But what happens when the tumor comes back? Has the tumor changed? And if so, how? These were questions that intrigued TGen Assistant Professor Floris Barthel, M.D. In particular, his latest research focuses on the effects of radiotherapy on the cancer tumor. What is different in the DNA of the first tumor compared to the normal DNA, and what is different in the DNA of the second tumor compared to the first tumor? How does treatment affect the DNA of these tumors over time? On this episode of TGen Talks, Dr. Barthel discusses how his work has shown that radiotherapy, while highly beneficial, appears to create breaks in the DNA and instead of dying, the cancer cell repairs itself, which alters the tumor make-up upon recurrence. He cautions there is still much to discover, but if successful, it could help identify those relapsed patients resistant to further radiotherapy and allow treating physicians to suggest an alternate course of treatment.
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83 حلقات
Manage episode 307856760 series 1936276
المحتوى المقدم من TGen Talks. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرة بواسطة TGen Talks أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.
Genomic analysis of a cancer tumor is fairly common these days. Researchers sequence and compare a patient’s non-cancerous DNA with their tumor DNA to identify changes that may allow a patient to receive medicine that specifically targets those changes. But what happens when the tumor comes back? Has the tumor changed? And if so, how? These were questions that intrigued TGen Assistant Professor Floris Barthel, M.D. In particular, his latest research focuses on the effects of radiotherapy on the cancer tumor. What is different in the DNA of the first tumor compared to the normal DNA, and what is different in the DNA of the second tumor compared to the first tumor? How does treatment affect the DNA of these tumors over time? On this episode of TGen Talks, Dr. Barthel discusses how his work has shown that radiotherapy, while highly beneficial, appears to create breaks in the DNA and instead of dying, the cancer cell repairs itself, which alters the tumor make-up upon recurrence. He cautions there is still much to discover, but if successful, it could help identify those relapsed patients resistant to further radiotherapy and allow treating physicians to suggest an alternate course of treatment.
…
continue reading
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