Ep. 66: Lithium Orotate for Anxiety and Brain Health with Daniel Rash

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Notes: NP03, a Microdose Lithium Formulation, Blunts Early Amyloid Post-Plaque Neuropathology in McGill-R-Thy1-APP Alzheimer-Like Transgenic Rats: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad190862 Can lithium halt progression of Alzheimer's disease?: https://www.sciencedaily.com/releases/2020/01/200125090727.htm Microdose Lithium Treatment Reduced Inflammatory Factors and Neurodegeneration in Organotypic Hippocampal Culture of Old SAMP-8 Mice: https://pubmed.ncbi.nlm.nih.gov/32642922/ Low-dose Lithium treatment for agitation and psychosis in Alzheimer’s disease and Frontotemporal dementia: A case series: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322244/ Lithium Orotate Stops Alzheimers: https://beforeitsnews.com/eu/2012/12/lithium-orotate-stops-alzheimers-2488838.html?utm_source=dlvr.it&utm_medium=twitter Lithium Orotate Risks: https://www.superfoodly.com/lithium-orotate/ On the Physiological function of lithium from a psychiatric viewpoint: https://pubmed.ncbi.nlm.nih.gov/11601880/ The Faces of Mania: The Legacy of Athanasios Koukopoulos: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405619/ The History of Lithium Therapy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712976/ History of the Introduction of Lithium into Medicine and Psychiatry: http://inhn.org/books/books/johan-schioldann-history-of-the-introduction-of-lithium-into-medicine-and-psychiatry-birth-of-modern-psychopharmacology-1949-reviewed-by-barry-blackwell.html Lithium increases N-acetyl-aspartate in the human brain: https://pubmed.ncbi.nlm.nih.gov/10913502/ N-acetylaspartate concentration in corpus callosum is positively correlated with intelligence in adolescents: https://pubmed.ncbi.nlm.nih.gov/21983183/ A Role in Neuroprotection against N-methyl-D-aspartate receptor-mediated excitotoxicity https://www.sciencedirect.com/science/article/pii/S0014579303001674 Neuroplasticity via glycogen synthase kinase-3beta, beta-catenin, and neurotrophin cascades: https://pubmed.ncbi.nlm.nih.gov/19423950/ Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?: https://pubmed.ncbi.nlm.nih.gov/10509176/ Lithium in drinking water and the incidences of crimes, suicides, and arrests related to drug addictions: https://pubmed.ncbi.nlm.nih.gov/1699579/ Lithium orotate in the treatment of alcoholism and related conditions: https://pubmed.ncbi.nlm.nih.gov/3718672/ Reduced Serotonin Reuptake Transporter (SERT) Function Causes Insulin Resistance and Hepatic Steatosis Independent of Food Intake: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297606/ Medications for Mental Health Treatment: https://dualdiagnosis.org/mental-health-and-addiction/medications/ Long-Term Lithium Treatment Causes Serotonin Receptor Down-Regulation via Serotonergic Presynapses in Rat Brain: https://www.karger.com/Article/PDF/118292 Mutation links bipolar disorder to mitochondrial disease: https://www.eurekalert.org/pub_releases/2018-06/r-mlb060818.php Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder: https://www.nature.com/articles/s41380-018-0074-9 Dietary amino acids and brain function: https://pubmed.ncbi.nlm.nih.gov/7903674/ Research explains lithium’s dual anti-manic/ anti-depressive effect: https://news.wisc.edu/research-explains-lithiums-dual-anti-manic-anti-depressive-effect/ Orotic Acid: Why it is Important to Understand Its Role in Metabolism: https://www.omicsonline.org/open-access/orotic-acid-why-it-is-important-to-understand-its-role-in-metabolism-2168-9652-1000e157.php?aid=90853 Nutritional therapies for mental disorders: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248201/ Products: Lithium Orotate: https://amzn.to/2XKCgVd Lithia Water(Lithium Chloride): https://amzn.to/33HBufz Ionic Lithium (Lithium Chloride): https://amzn.to/33JtFWz Music by Jenny Jahlee from Live at KBOO