Rick Caruso on LA’s Wildfires, Policy Failures, and the Path Forward

No Priors: Artificial Intelligence | Technology | Startups

No Priors: Artificial Intelligence | Technology | Startups

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<div class="span index">1</div> <span><a class="" data-remote="true" data-type="html" href="/series/biscuits-jam-2787342">Biscuits & Jam</a></span>

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Biscuits & Jam

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منذ 3 أياممنذ 3d ago

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In the South, food and music go hand in hand. They define much of what we think of as Southern culture, and they say a lot about our past, our present, and our future. Each week, Sid Evans, Editor in Chief of Southern Living, sits down with musicians, chefs, and other Southern icons to hear the stories of how they grew up, what inspires them, and why they feel connected to the region. Through honest conversations, Sid explores childhood memories, the family meals they still think about, and the intersection of food and music in their lives. Always surprising, always engaging, Biscuits & Jam is a celebration of the South—and the people who are moving it forward every day. New episodes every Tuesday.

منذ عام واحد 27:11

MP3•منزل الحلقة

0:00 Introduction

0:56 Caruso’s history in business and public service

3:36 Failures in fire prevention and response

5:58 How Caruso’s properties survived

8:26 Water shortages and infrastructure failures

9:47 Arson, looting, and crime in LA

15:03 Rebuilding

20:50 Allocating California’s resources effectively

26:15 Caruso’s future plans

106 حلقات

#Science #Tech #Entrepreneur #Business #Convicted #Pod People

No Priors: Artificial Intelligence | Technology | Startups

Rick Caruso on LA’s Wildfires, Policy Failures, and the Path Forward

No Priors: Artificial Intelligence | Technology | Startups

75 subscribers

published منذ عام واحد

MP3•منزل الحلقة

Show Notes

0:00 Introduction

0:56 Caruso’s history in business and public service

3:36 Failures in fire prevention and response

5:58 How Caruso’s properties survived

8:26 Water shortages and infrastructure failures

9:47 Arson, looting, and crime in LA

15:03 Rebuilding

20:50 Allocating California’s resources effectively

26:15 Caruso’s future plans

106 حلقات

#Science #Tech #Entrepreneur #Business #Convicted #Pod People

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No Priors: Artificial Intelligence | Technology | Startups

1
National Security Strategy and AI Evals on the Eve of Superintelligence with Dan Hendrycks 36:24

منذ 1 day36:24

36:24

This week on No Priors , Sarah is joined by Dan Hendrycks, director of the Center of AI Safety. Dan serves as an advisor to xAI and Scale AI. He is a longtime AI researcher, publisher of interesting AI evals such as "Humanity's Last Exam," and co-author of a new paper on National Security " Superintelligence Strategy " along with Scale founder-CEO Alex Wang and former Google CEO Eric Schmidt. They explore AI safety, geopolitical implications, the potential weaponization of AI, along with policy recommendations. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @DanHendrycks Show Notes: 0:00 Introduction 0:36 Dan’s path to focusing on AI Safety 1:25 Safety efforts in large labs 3:12 Distinguishing alignment and safety 4:48 AI’s impact on national security 9:59 How might AI be weaponized? 14:43 Immigration policies for AI talent 17:50 Mutually assured AI malfunction 22:54 Policy suggestions for current administration 25:34 Compute security 30:37 Current state of evals…

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منذ 7 أيام40:32

40:32

This week on No Priors , Sarah sits down with Noubar Afeyan, Co-founder and CEO of Flagship Pioneering, the biotech firm behind groundbreaking companies like Moderna. They explore how Flagship creates the conditions for scientific breakthroughs, tackles regulatory uncertainty, and pushes the boundaries of discovery. Noubar shares insights on AI’s role in healthcare, the challenges of bringing new therapies to market, and lessons learned from past pandemics. He also discusses Flagship’s platform approach to biotech innovation and introduces the idea of polyintelligence. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @NoubarAfeyan Show Notes: 0:00 Introduction 0:48 Founding Flagship 5:51 Fostering environments for emergence 11:17 Expanding into new frontiers 14:26 Developing technology amid regulatory uncertainty and risk 19:12 How Flagship has evolved 22:47 AI applications in healthcare 27:30 Bottlenecks in bringing new therapies to market 32:20 Lessons for the next pandemic 34:11 Building a platform 38:10 Polyintelligence…

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منذ 9 أيام57:40

57:40

On this week’s episode of No Priors , Sarah Guo is joined by leading members of the teams at Vevo Therapeutics and the Arc Institute – Nima Alidoust, CEO/Co-Founder at Vevo Therapeutics; Johnny Yu, CSO/Co-Founder at Vevo Therapeutics; Patrick Hsu, CEO/Co-Founder at Arc Institute; Dave Burke, CTO at Arc Institute; and Hani Goodarzi, Core Investigator at Arc Institute. Predicting protein structure (AlphaFold 3, Chai-1, Evo 2) was a big AI/biology breakthrough. The next big leap is modeling entire human cells—how they behave in disease, or how they respond to new therapeutics. The same way LLMs needed enormous text corpora to become truly powerful, Virtual Cell Models need massive, high-quality cellular datasets to train on. In this episode, the teams discuss the groundbreaking release of the Tahoe-100M single cell dataset, Arc Atlas, and how these advancements could transform drug discovery. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @Nalidoust | @IAmJohnnyYu | @PDHsh | @Davey_Burke | @Genophoria Download the Tahoe Dataset Show Notes: 0:00 Introduction 1:40 Significance of Tahoe-100M dataset 4:22 Where we are with virtual cell models and protein language models 10:26 Significance of perturbational data 17:39 Challenges and innovations in data collection 24:42 Open sourcing and community collaboration 33:51 Predictive ability and importance of virtual cell models 35:27 Drug discovery and virtual cell models 44:27 Platform vs. single hypothesis companies 46:05 Rise of Chinese biotechs 51:36 AI in drug discovery…

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منذ 14 يومًا38:14

38:14

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منذ 20 يومًا49:35

49:35

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1
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منذ 27 يومًا22:32

22:32

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No Priors: Artificial Intelligence | Technology | Startups

1
Rick Caruso on LA’s Wildfires, Policy Failures, and the Path Forward 27:11

منذ 5 weeks27:11

27:11

This week on No Priors, Elad sits down with Rick Caruso, LA real estate developer and runner-up in the 2022 mayoral race. With experience serving under three LA mayors, as well as on the police commission and the board of water and power, Rick offers a unique perspective on the systemic failures that contributed to the devastation of the January 2025 wildfires in communities like the Palisades and Altadena. He discusses the steps he took to build more resilient infrastructure in his properties and how California can rebuild smarter to better prepare for future disasters. They also explore the state’s water management, rising crime, and how to leverage California’s vast natural resources and budget to create a better future for all residents. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @RickCarusoLA Show Notes 0:00 Introduction 0:56 Caruso’s history in business and public service 3:36 Failures in fire prevention and response 5:58 How Caruso’s properties survived 8:26 Water shortages and infrastructure failures 9:47 Arson, looting, and crime in LA 15:03 Rebuilding 20:50 Allocating California’s resources effectively 26:15 Caruso’s future plans…

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1
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منذ 6 weeks37:59

37:59

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منذ 7 weeks30:09

30:09

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منذ 8 weeks23:36

23:36

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منذ 10 weeks27:07

27:07

2024 has been a year of transformative technological progress, marked by conversations that have reshaped our understanding of AI's evolution and what lies ahead. Throughout the year, Sarah and Elad have had the privilege of speaking with some of the brightest minds in the field. As we look back on the past months, we’re excited to share highlights from some of our favorite No Priors podcast episodes. Featured guests include Jensen Huang (Nvidia), Andrej Karpathy (OpenAI, Tesla), Bret Taylor (Sierra), Aditya Ramesh, Tim Brooks, and Bill Peebles (OpenAI’s Sora Team), Dmitri Dolgov (Waymo), Dylan Field (Figma), and Alexandr Wang (Scale). Want to dive deeper? Listen to the full episodes here: NVIDIA's Jensen Huang on AI Chip Design, Scaling Data Centers, and his 10-Year Bet No Priors Ep. 89 | With NVIDIA CEO Jensen Huang The Road to Autonomous Intelligence, With Andrej Karpathy from OpenAI and Tesla No Priors Ep. 80 | With Andrej Karpathy from OpenAI and Tesla Transforming Customer Service through Company Agents, with Sierra’s Bret Taylor No Priors Ep. 82 | With CEO of Sierra Bret Taylor OpenAI’s Sora team thinks we’ve only seen the "GPT-1 of video models" No Priors Ep.61 | OpenAI's Sora Leaders Aditya Ramesh, Tim Brooks and Bill Peebles Waymo’s Journey to Full Autonomy: AI Breakthroughs, Safety, and Scaling No Priors Ep. 87 | With Co-CEO of Waymo Dmitri Dolgov Designing the Future: Dylan Field on AI, Collaboration, and Independence No Priors Ep. 55 | With Figma CEO Dylan Field The Data Foundry for AI with Alexandr Wang from Scale No Priors Ep. 65 | With Scale AI CEO Alexandr Wang Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil Show Notes: 0:00 Introduction 0:15 Jensen Huang on building at data-center scale 4:00 Andrej Karpathy on the AI exo-cortex, model control, and a shift to smaller models 7:14 Bret Taylor on the agentic future of business interactions 11:17 OpenAI’s Sora team on visual models and their role in AGI 15:53 Waymo’s Dmitri Dolgov on bridging the gap to full autonomy and the challenge of 100% accuracy 19:00 Figma’s Dylan Field on the future of interfaces and new modalities 23:29 Scale AI’s Alexandr Wang on the journey to AGI 26:29 Outro…

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منذ 11 weeks31:18

31:18

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منذ 12 weeks42:21

42:21

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1
Bolt’s Eric Simons on Enabling Everyone to Generate Websites with AI 38:17

منذ 13 weeks38:17

38:17

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1
Model Plateaus and Enterprise AI Adoption with Cohere's Aidan Gomez 44:15

منذ 15 weeks44:15

44:15

In this episode of No Priors , Sarah is joined by Aidan Gomez, cofounder and CEO of Cohere. Aidan reflects on his journey to co-authoring the groundbreaking 2017 paper, “Attention is All You Need,” during his internship, and shares his motivations for building Cohere, which delivers AI-powered language models and solutions for businesses. The discussion explores the current state of enterprise AI adoption and Aidan’s advice for companies navigating the build vs. buy decision for AI tools. They also examine the drivers behind the flattening of model improvements and discuss where large language models (LLMs) fall short for predictive tasks. The conversation explores what the market has yet to account for in the rapidly evolving AI ecosystem, as well as Aidan’s personal perspectives on AGI—what it might look like and when it could arrive. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @AidanGomez Show Notes: 0:00 Introduction 0:36 Co-authoring “Attention is all you need” 2:27 Leaving Google and founding Cohere 4:04 Cohere’s mission and models 6:15 Pitfalls of current AI 8:14 How enterprises are deploying AI today 10:58 Build vs. buy strategy for AI tools 14:37 Barriers to enterprise adoption 20:04 Which types of companies should pretrain models? 24:25 Addressing flaws in open-source models 25:12 Current and expected progress in scaling laws 29:54 Advances in multi-step problem solving and reasoning 32:29 Key drivers behind the flattening curve of model improvements 36:25 Exploring AGI 39:59 Limitations of LLMs 42:10 What the market has mispriced…

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No Priors: Artificial Intelligence | Technology | Startups « » Rick Caruso on LA’s Wildfires, Policy Failures, and the Path Forward

Rick Caruso on LA’s Wildfires, Policy Failures, and the Path Forward

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Rick Caruso on LA’s Wildfires, Policy Failures, and the Path Forward