Astellas Pharma’s Approach to Cell and Gene Therapy

Life Sciences 360

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المحتوى المقدم من Harsh Thakkar. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرة بواسطة Harsh Thakkar أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.

Exile

1
Episode 10: From Refugee to Radical 44:09

منذ 2 years44:09

التشغيل لاحقا

قوائم

إعجاب

احب

44:09

When a young Eva Kollisch arrives as a refugee in New York in 1940, she finds a community among socialists who share her values and idealism. She soon discovers ‘the cause’ isn’t as idyllic as it seems. Little does she know this is the beginning of a lifelong commitment to activism and her determination to create radical change in ways that include belonging, love and one's full self. In addition to Eva Kollisch’s memoirs Girl in Movement (2000) and The Ground Under My Feet (2014), LBI’s collections include an oral history interview with Eva conducted in 2014 and the papers of Eva’s mother, poet Margarete Kolllisch, which document Eva’s childhood experience on the Kindertransport. Learn more at www.lbi.org/kollisch . Exile is a production of the Leo Baeck Institute , New York | Berlin and Antica Productions . It’s narrated by Mandy Patinkin. Executive Producers include Katrina Onstad, Stuart Coxe, and Bernie Blum. Senior Producer is Debbie Pacheco. Associate Producers are Hailey Choi and Emily Morantz. Research and translation by Isabella Kempf. Sound design and audio mix by Philip Wilson, with help from Cameron McIver. Theme music by Oliver Wickham. Voice acting by Natalia Bushnik. Special thanks to the Kollisch family for the use of Eva’s two memoirs, “Girl in Movement” and “The Ground Under My Feet”, the Sophia Smith Collection at Smith College and their “Voices of Feminism Oral History Project”, and Soundtrack New York.…

منذ عام واحد 36:11

MP3•منزل الحلقة

In this episode of LifeSciences 360, we dive into the fascinating world of cell and gene therapy manufacturing with Carlos Yuraszeck. With over 16 years of experience, Carlos shares his deep insights into the unique challenges, opportunities, and innovations in the field, offering a detailed look into what it takes to bring life-saving therapies to patients. We cover everything from the design of manufacturing facilities to the complexities of quality systems, patient-centric innovations, and the future of allogeneic therapies.
If you're interested in the life sciences, cell and gene therapy, or just curious about cutting-edge advancements in medicine, this episode is for you!
Chapters:
00:00 - Intro
00:02 - Understanding Cell and Gene Therapy Facilities
00:09 - Challenges in Cell Therapy Facility Design
00:26 - Automation in Manufacturing
00:42 - Balancing Quality, Cost, and Time
00:53 - Patient-Centric Manufacturing
01:21 - Guest Introduction: Carlos Yuraszeck
02:06 - Carlos’s Journey in Cell and Gene Therapy
03:21 - Unique Factors in Facility Design
04:14 - Making Facilities Operational
05:09 - Subscription Appeal
06:13 - Autologous vs. Allogeneic Cell Therapies Explained
08:13 - Adjusting Processes Based on Patient Variability
09:37 - Stem Cell Derived Therapies
10:39 - Biotech Companies: Autologous or Allogeneic?
12:07 - Strategic Decisions in Facility Design
14:50 - Phase-Appropriate Quality Systems
16:45 - Regulatory Flexibility and Urgency for Patients
18:08 - Change Control in Early vs. Late Phases
19:02 - Batch Records and Operator Judgment
20:27 - Training Focus for Different Phases
22:38 - Balancing Regulatory Requirements and Innovation
24:32 - Risk Assessment Based on Patient Needs
26:18 - The Potential of CAR T Therapies
28:05 - The Allogeneic Space and Future Prospects
31:00 - The Transformative Impact of Cell Therapy
32:22 - Carlos’s Career Lessons and Fear of the Unknown
34:45 - Closing Remarks and Subscription Reminder
36:37 - Outro
---
🔗 Links Mentioned:
Connect with Carlos on LinkedIn:
https://www.linkedin.com/in/carlos-yuraszeck-5400091/
- Follow Life Sciences 360 on LinkedIn
(https://www.linkedin.com/company/life-sciences-360)
---
Subscribe to our podcast for more insights on life sciences:
🍎Apple podcast: https://apple.co/3RXPoS1
🟩 Spotify podcast: https://spoti.fi/3EbDZbr
💬 Let us know in the comments: Did you know worms could be this powerful?
👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences!
Make sure to subscribe for more industry insights, and don't forget to leave a comment or question for our guest, Carlos Yuraszeck!
---
#Celltherapy #GMPoperations #executivedirector #astellaspharma #CellTherapyManufacturing #facilitydesign #DesigningCell

For transcripts, check out the podcast website - www.lifesciencespod.com

75 حلقات

#Science #Biology #Harsh Thakkar #Life Sciences #Quality Management #Regulatory Compliance #Biotechnology #Pharmaceutical #Medical Device #Med Tech

Astellas Pharma’s Approach to Cell and Gene Therapy

Life Sciences 360

published منذ عام واحد

MP3•منزل الحلقة

For transcripts, check out the podcast website - www.lifesciencespod.com

75 حلقات

#Science #Biology #Harsh Thakkar #Life Sciences #Quality Management #Regulatory Compliance #Biotechnology #Pharmaceutical #Medical Device #Med Tech

كل الحلقات

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منذ 12 يومًا44:05

44:05

Have you ever wondered why marketing in the life sciences industry is so different from traditional marketing? In this episode, we dive deep into the power of science marketing, the impact of brand storytelling, and how companies can successfully position their products in a competitive market. From publishing content to collaboration with industry, we'll show you how to harness the power of science marketing for success. Why do some breakthrough innovations never reach their full potential, while others become industry leaders? Our guest, Elizabeth Chabe, is the CEO of High Touch Group and a leading expert in scientific marketing. She shares invaluable insights on how companies can build credibility, shorten sales cycles, and effectively communicate complex innovations to investors, researchers, and the public. We also explore: ✅ Why scientific breakthroughs fail without proper marketing ✅ The biggest mistakes life sciences companies make ✅ How to pitch complex ideas to experts & decision-makers ✅ The secret behind pharma ads & storytelling in healthcare ✅ How conferences & live demonstrations can transform your brand This episode is packed with expert strategies, real-world examples, and game-changing marketing insights for biotech, medtech, and pharma professionals. ⏱️ Chapters: 00:00 Introduction 02:24 Why Science Marketing is Crucial 05:38 How to Tailor Your Message for Experts 14:29 The ROI of Marketing – Why It’s a Game Changer 22:24 The Secret Behind Pharma Ads & Storytelling 27:31 A Genius Conference Marketing Strategy 32:25 The Future of Science Marketing & Live Engagement 35:04 Why Elizabeth Runs a Global Business 38:50 A Sneak Peek Into Her Book – The Giants Ladder 42:31 Final Thoughts & Takeaways 🔗 Links Mentioned: 📌 Connect with Elizabeth Chabe on LinkedIn: https://www.linkedin.com/in/eviselli/ 📌 Learn more about the work she does at High Touch Group 📌 Grab a copy of Elizabeth's book, The Giants Ladder For transcripts, check out the podcast website - www.lifesciencespod.com…

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منذ 19 يومًا37:44

37:44

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منذ 26 يومًا43:51

43:51

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How to Get Quick Access to GLP-1 Medications without Health Insurance ft. Dr. Jonathan Kaplan 41:10

منذ عام واحد41:10

41:10

In this episode of Life Sciences 360, we dive deep into the world of GLP-1 medications with Dr. Jonathan Kaplan. We discuss weight management, how these medications work, their impact beyond weight loss, and the ethical considerations surrounding their use. Dr. Kaplan shares his insights on the healthcare industry's evolving landscape, the economic implications, and why these medications are changing everything from cosmetic surgery to chronic disease management. Chapters: 00:00 Introduction 00:02 Dr. Jonathan Kaplan’s Background 00:16 Overview of GLP-1 Medications 00:25 The Significance of GLP-1s 00:35 Future FDA Approvals 00:51 Welcome to the Episode 01:12 Meet Dr. Jonathan Kaplan 01:19 Dr. Kaplan’s Journey into Weight Management 02:09 Early Days Before the GLP-1 Hype 02:30 Compounding Pharmacy and Medication Shortages 03:17 Success of the Weight Management Program 03:23 YouTube Subscriber Request 04:17 GLP-1 Mechanisms Explained 05:00 How GLP-1s Work in the Body 05:51 Historical Timeline of GLP-1 Medications 06:48 Semaglutide’s Evolution 07:23 The Rise of Ozempic and Wegovy 07:43 New Developments in Weight Management 08:54 Accidental Discoveries and Hormones 09:35 Significance of GLP-1 Discoveries 10:02 Medication Approval and Insurance Hurdles 10:43 Patient Expectations vs. Reality 12:09 Misconceptions About Weight Loss 12:51 Other Health Benefits Beyond Weight Loss 14:10 The Complex Psychology of Weight Loss 15:16 Importance of Diet and Exercise 16:10 How to Get Access to These Medications 18:02 Transparent Pricing Model 20:19 Maintenance and Subscription Options 22:04 Challenges with Insurance 23:21 Insurance Pitfalls and Complications 24:42 Speed of Access and Medication Availability 25:41 Ethical Considerations in Prescribing GLP-1s 27:28 Balancing Ethics and Accessibility 29:35 Broader Impact on Public Health and Economics 30:35 Transforming Healthcare Through Weight Management 32:12 Future of GLP-1 Medications 33:58 Changing Consumer Preferences and Food Labels 35:51 Reflections on Dr. Kaplan’s Career 37:06 Closing Remarks 39:11 Key Takeaway on Safe Access 41:03 Conclusion and Gratitude 🔗 Links Mentioned: Dr. Jonathan Kaplan, Founder and CEO at Build My Health Linkedin - (https://www.linkedin.com/in/buildmybod/) - Visit Dr. Jonathan Kaplan’s website: (https://www.drwell.com) - Website : (https://www.buildmybod.com/author/kaplan/) - Follow Dr. Well on TikTok and Instagram: (https://www.tiktok.com/@drwellrx) - Contact Dr. Jonathan Kaplan: jkaplan@drwell.com - Follow Life Sciences 360 on LinkedIn (https://www.linkedin.com/company/life-sciences-360) --- Subscribe to our podcast for more on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr #GLP1 #WeightLoss #HealthCare #LifeSciences360 #DrJonathanKaplan #Ozempic #Wegovy #WeightManagement #HealthAndWellness #GLP1Medications #Type2Diabetes #ObesityTreatment #MedicalPodcast #HealthyLiving #Pharmaceuticals #Semaglutide #Medicine #SciencePodcast #MedicalResearch #PreventiveHealth For transcripts, check out the podcast website - www.lifesciencespod.com…

1
Astellas Pharma’s Approach to Cell and Gene Therapy 36:11

منذ عام واحد36:11

36:11

In this episode of LifeSciences 360, we dive into the fascinating world of cell and gene therapy manufacturing with Carlos Yuraszeck. With over 16 years of experience, Carlos shares his deep insights into the unique challenges, opportunities, and innovations in the field, offering a detailed look into what it takes to bring life-saving therapies to patients. We cover everything from the design of manufacturing facilities to the complexities of quality systems, patient-centric innovations, and the future of allogeneic therapies. If you're interested in the life sciences, cell and gene therapy, or just curious about cutting-edge advancements in medicine, this episode is for you! Chapters: 00:00 - Intro 00:02 - Understanding Cell and Gene Therapy Facilities 00:09 - Challenges in Cell Therapy Facility Design 00:26 - Automation in Manufacturing 00:42 - Balancing Quality, Cost, and Time 00:53 - Patient-Centric Manufacturing 01:21 - Guest Introduction: Carlos Yuraszeck 02:06 - Carlos’s Journey in Cell and Gene Therapy 03:21 - Unique Factors in Facility Design 04:14 - Making Facilities Operational 05:09 - Subscription Appeal 06:13 - Autologous vs. Allogeneic Cell Therapies Explained 08:13 - Adjusting Processes Based on Patient Variability 09:37 - Stem Cell Derived Therapies 10:39 - Biotech Companies: Autologous or Allogeneic? 12:07 - Strategic Decisions in Facility Design 14:50 - Phase-Appropriate Quality Systems 16:45 - Regulatory Flexibility and Urgency for Patients 18:08 - Change Control in Early vs. Late Phases 19:02 - Batch Records and Operator Judgment 20:27 - Training Focus for Different Phases 22:38 - Balancing Regulatory Requirements and Innovation 24:32 - Risk Assessment Based on Patient Needs 26:18 - The Potential of CAR T Therapies 28:05 - The Allogeneic Space and Future Prospects 31:00 - The Transformative Impact of Cell Therapy 32:22 - Carlos’s Career Lessons and Fear of the Unknown 34:45 - Closing Remarks and Subscription Reminder 36:37 - Outro --- 🔗 Links Mentioned: Connect with Carlos on LinkedIn: https://www.linkedin.com/in/carlos-yuraszeck-5400091/ - Follow Life Sciences 360 on LinkedIn (https://www.linkedin.com/company/life-sciences-360) --- Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 💬 Let us know in the comments: Did you know worms could be this powerful? 👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences! Make sure to subscribe for more industry insights, and don't forget to leave a comment or question for our guest, Carlos Yuraszeck! --- #Celltherapy #GMPoperations #executivedirector #astellaspharma #CellTherapyManufacturing #facilitydesign #DesigningCell For transcripts, check out the podcast website - www.lifesciencespod.com…

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ISPE’s Role in Shaping the Future of mRNA and Personalized Medicine 34:03

منذ عام واحد34:03

34:03

In this episode of Life Sciences 360, we dive into the evolution of pharmaceutical and biotech manufacturing with our guest, Scott, a seasoned expert with nearly 30 years of experience working with industry giants like Novartis, Biogen, Thermo Fisher, and Merck. Scott shares insights on cell culture technology, mRNA vaccines, and the challenges and innovations in scaling biotech facilities. Discover the impact of collaboration and how organizations like the International Society for Pharmaceutical Engineering (ISPE) are transforming the landscape. Chapters : 00:00 - Introduction to Vaccine Technologies 00:14 - Importance of Collaboration in Pharma Manufacturing 00:22 - The Role of Technology Ecosystems 00:30 - Scott’s Experience with ISPE 00:46 - Motivation Behind Pharma & Biotech Careers 01:09 - Welcoming Scott to Life Sciences 360 01:19 - Scott’s Background & Industry Experience 01:45 - Integrating Technology in Pharmaceutical Facilities 01:59 - Scott’s Current Role & Unique Challenges 02:18 - Interview Kickoff: Scott’s Career Insights 03:11 - The Evolution of Drug Manufacturing 03:39 - Insights for Non-Pharma Audiences 03:59 - Changes in Vaccine Manufacturing Over the Years 04:40 - mRNA Technology and Its Impact 05:05 - Encouraging Viewers to Subscribe 05:59 - Driving Innovation in Manufacturing Facilities 07:01 - Challenges in Scaling New Therapies 08:17 - Overcoming Challenges in New Tech Implementation 09:03 - The Role of Technology Vendors 10:08 - Advancements in Manufacturing Technology 11:02 - Evolution of Biotech Processes 12:09 - Consulting in Cell and Gene Therapy 13:02 - The Infancy of Cell and Gene Therapy 13:23 - Introduction to SoulVentum 14:01 - Separation from 3M and Vision for SoulVentum 15:01 - Scott’s Role at SoulVentum 15:33 - Scott’s Contributions to ISPE 17:18 - Identifying Award-Winning Facilities 18:39 - ISPE Facility of the Year Criteria 20:18 - Global Reach of ISPE Submissions 21:41 - Geographical Insights Post-Pandemic 22:47 - The Role of ISPE in Pharma Collaboration 23:31 - ISPE Communities of Practice 24:47 - Forums & Conferences by ISPE 26:19 - Local ISPE Chapters & Regional Support 26:58 - Scott’s Take on Industry Networking 28:05 - The Importance of Professional Networks 29:05 - Advice on Building a Career in Pharma 30:21 - Scott’s Mission in the Industry 31:42 - Personal Impact of the Work in Pharma 32:26 - Patient Stories and Their Motivational Impact 33:22 - Closing Thoughts & How to Connect with Scott 🔗 Links Mentioned: Connect with Scott on LinkedIn: https://www.linkedin.com/in/scott-billman-a865093b/ Learn more about ISPE: https://ispe.org/ - Follow Life Sciences 360 on LinkedIn (https://www.linkedin.com/company/life-sciences-360) --- Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 💬 Let us know in the comments: Did you know worms could be this powerful? 👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences! #LifeSciences360 #PharmaceuticalIndustry #Biotech #PharmaManufacturing #DrugDevelopment #mRNA #CellTherapy #GeneTherapy #ISPE #BiotechInnovation #PharmaceuticalEngineering #VaccineTechnology #PharmaCareers #PharmaInnovation #LifeSciences #SoulVentum #HealthcareManufacturing #BiotechIndustry #PharmaTechnology #Industry4 For transcripts, check out the podcast website - www.lifesciencespod.com…

1
Balancing Leadership Roles in a High-Stakes Industry with Taggart McGurrin 30:00

منذ عام واحد30:00

30:00

Welcome to another episode of Life Sciences 360! Today, we're diving into the intricate world of life sciences leadership with a special guest who's worn nearly every hat in the industry—Taggart McGurrin. Starting in finance, transitioning to law, and tackling leadership roles across strategy, operations, and regulatory affairs, Taggart McGurrin brings a unique perspective on how to navigate the high-stakes environment of life sciences. In this episode, we cover: The Complexities of Life Sciences: Taggart McGurrin explains why this industry has more risk areas than most, from regulatory hurdles to financial pressures. Triple Threat in Leadership: Discover Taggart's approach to balancing “What you have, what you need, and what you want” for effective decision-making. Navigating the CFO/COO Role: Taggart shares insights on managing dual executive roles, emphasizing the importance of detail, resilience, and creative pragmatism. Overcoming Financial Hurdles: Insights on cash flow challenges and how proper planning and investor relations drive success. Unique Challenges in Life Sciences: The balancing act between meeting regulatory demands and fostering innovation. Whether you’re a leader in life sciences, considering a C-level role, or just curious about this industry, this episode is packed with practical insights! Chapters: 00:00 - Intro 01:00 - The Life Sciences Landscape 03:30 - Importance of Patient-Centric Leadership 10:00 - The Role of Detail in Executive Leadership 17:00 - Managing Financial Pressures in Life Sciences 22:00 - Navigating Regulatory Challenges 27:00 - Raising Capital in Life Sciences 29:00 - Final Takeaways If you’re looking to understand the unique challenges and leadership dynamics within life sciences, this is a must-watch! Don’t forget to subscribe for more content on leadership, innovation, and life sciences trends. 💡 Connect with Tagg McGurrin: https://www.linkedin.com/in/taggartmcgurrin/ - Follow Life Sciences 360 on LinkedIn (https://www.linkedin.com/company/life-sciences-360) --- Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 💬 Let us know in the comments: Did you know worms could be this powerful? 👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences! #LifeSciences360 #PharmaceuticalLeadership #LifeSciencesIndustry #HealthcareLeadership #ExecutiveInsights #PharmaInnovation #LeadershipInLifeSciences #FinanceInLifeSciences #RegulatoryChallenges #LifeSciencesCareers #CFOCOO #TripleThreatLeadership #FDACompliance #LifeSciencesPodcast #PharmaRisks #PatientCentricLeadership #CorporateStrategy #HealthcareInnovation #BiotechLeadership #InvestmentInPharma For transcripts, check out the podcast website - www.lifesciencespod.com…

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Why Antimicrobial Resistance Is the Biggest Challenge in Public Health 41:08

منذ عام واحد41:08

41:08

In this episode of Life Sciences 360, host Harsh Thakkar sits down with Marc Sheetz, Associate Dean of Research at Midwestern University's College of Pharmacy, to discuss the growing concern of antimicrobial resistance and the field of pharmacometrics. Marc sheds light on how pharmacometrics is shaping the future of medicine by using predictive models to personalize dosing, making drug treatments more effective while reducing toxicity. This episode dives deep into the intersection of pharmacometrics, AI, and machine learning, revealing how the future of patient care and treatment is rapidly evolving. Marc also shares insights from his current research in the infectious disease space, including his work with pediatric ICU patients. Chapters: 00:00 Introduction 00:03 Antibiotic Toxicity and Population Models 01:02 The Importance of Antibiotics and Public Health Challenges 01:22 Introduction to Pharmacometric Science 03:12 Using Data in Medicine for Future Predictions 06:01 Tailoring Drug Dosages for Individuals 09:36 The Global Variation in Drug Dosages and Challenges 14:44 The Future of Personalized Medicine and Precision Dosing 21:39 The Intersection of AI, Machine Learning, and Pharmacometrics 26:35 The Role of Technology in Medicine 30:01 How Dosing Software and AI Are Enhancing Patient Care 36:54 Innovation and Research Trends in Medicine - Connect with Marc Sheetz on Twitter: (https://twitter.com/IDPharmacometrics) - Learn more about Midwestern University: (https://www.midwestern.edu) - Follow Life Sciences 360 on LinkedIn (https://www.linkedin.com/company/life-sciences-360) --- Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 💬 Let us know in the comments: Did you know worms could be this powerful? 👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences! #Pharmacokinetics #Pharmacodynamics #AntibioticResistance, #AntimicrobialResistance #AIinHealthcare #PrecisionMedicine #PersonalizedMedicine #Infectious #DiseaseResearch For transcripts, check out the podcast website - www.lifesciencespod.com…

1
The Secret to Better Medications: Standardizing Pharmacogenomics (PGx) Testing 29:59

منذ عام واحد29:59

29:59

Imagine knowing how your body will respond to a medication before you even take it! In this episode, Harsh Thakkar interviews Sarah Rogers, co-founder and president of the American Society of Pharmacovigilance (ASP) and an Assistant Professor at Texas A&M. Together, they dive deep into the fascinating world of pharmacogenomics—how your genetic makeup affects your response to medications. They discuss the challenges of pharmacogenomic testing, real-world examples of adverse drug reactions, and the future of personalized medicine. Chapters: 00:00 - Intro 00:16 - Breaking Down Pharmacogenomics 01:39 - Guest Introduction: Sarah Rogers 02:18 - Explaining Pharmacogenomics to a Child 03:24 - Sarah's Start in Pharmacogenomics 04:54 - The Power of Pharmacogenomics 07:00 - Pharmacogenomics Clinic at Texas A&M 09:02 - Challenges of Standardizing PGX Testing 11:14 - The Ideal Pharmacogenomics Workflow 13:39 - Real-World Example of PGX in Action 15:44 - Importance of Integrating PGX into EHR 20:24 - AI and Digital Twins in Pharmacogenomics 21:52 - Lessons Learned in Pharmacogenomics 24:46 - Looking to the Future of Personalized Medicine 28:18 - Final Takeaway 30:22 - Outro Connect with Sarah Rogers: - LinkedIn: (https://www.linkedin.com/company/american-society-of-pharmacovigilance) - STRIPE Initiative LinkedIn: (https://www.linkedin.com/company/stripe-pharmacogenomics) - Twitter: (https://twitter.com/amsocietypharm) - Newsletter signup for the American Society of Pharmacovigilance: https://www.stopadr.org/ Here are links for some of the information that I mentioned during our meeting: - STRIPE Annual Meeting and Consensus Workshop - (https://www.usp.org/node/289416) - Collaborative Communities: Addressing Health Care Challenges Together (https://www.fda.gov/about-fda/cdrh-strategic-priorities-and-updates/collaborative-communities-addressing-health-care-challenges-together) - Standardizing Laboratory Practices in Pharmacogenomics (STRIPE) Collaborative Community - (https://stopadr.org/stripe) - Texas A&M Interprofessional Pharmacogenomics (IPGx) Clinic - (https://ibt.tamu.edu/cores/Texas%20ClinicoGenomics/Texas%20ClinicoGenomics.html) - National Action Plan for Adverse Drug Event Prevention - (https://health.gov/sites/default/files/2019-09/ADE-Action-Plan-508c.pdf) - Figure showing Stakeholders Involved in the Lifecycle of a Pharmacogenomics Test (https://www.nature.com/articles/s41397-024-00345-y/figures/1) - Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 💬 Let us know in the comments: Did you know worms could be this powerful? 👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences! --- #Pharmacogenomics #PersonalizedMedicine #SarahRogers #PGX #GeneticMakeup For transcripts, check out the podcast website - www.lifesciencespod.com…

1
Life Sciences Marketing Agency CEO on How to Combine Storytelling and Science for Impact 36:46

منذ عام واحد36:46

36:46

In this episode, Harsh Thakkar welcomes David Ormesher, CEO of CG Life, a leading marketing agency in the life sciences and pharmaceutical sectors. David shares over 30 years of experience in life science marketing and storytelling. From startups to large enterprises, CG Life helps companies blend complex science with compelling stories to resonate with patients, healthcare professionals, and investors. David discusses his entrepreneurial journey, how CG Life specializes in biopharmaceutical marketing, and key insights into building an agency that bridges the gap between science and storytelling. He also shares the strategic importance of focusing on the patient journey, how to scale marketing for companies of all sizes, and the role of digital platforms in the ever-evolving landscape of pharma and biotechnology marketing. Chapters: 00:00 - Introduction 00:09 - The Importance of Storytelling in Life Sciences 01:00 - David’s Journey into Life Science Marketing 02:00 - Starting CG Life and its Evolution 05:00 - Combining Science and Storytelling 08:00 - Challenges and Opportunities in Biopharma Marketing 10:00 - CG Life's Growth Strategy and Key Acquisitions 13:00 - Leveraging Social Media and Digital Platforms in Pharma 17:00 - Storytelling for Different Audiences: Patients, HCPs, and Investors 22:00 - Case Study: Terran Biosciences – Building Market Visibility 24:00 - Case Study: Novo Nordisk – Digital Customer Experience for HCPs 30:00 - Advice for Entrepreneurs Starting a Marketing Agency 34:00 - Lessons Learned from David’s Entrepreneurial Journey 36:00 - Building a Strong Team for Success 37:00 - Final Thoughts and Call to Action Don’t forget to subscribe and share your thoughts in the comments! Let us know what topics or guests you want to see next. --- Links: Visit CG Life: (https://www.cglife.com) Connect with David Ormesher on LinkedIn: (https://www.linkedin.com/in/davidormesher) - Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 💬 Let us know in the comments: Did you know worms could be this powerful? 👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences! #LifeSciences #PharmaMarketing #Biotech #Entrepreneurship #PatientJourney #StorytellingInScience #MarketingStrategy #DigitalHealth #HealthcareMarketing #CGLife #Biopharma #PharmaceuticalIndustry #HealthcareInnovation #MarketingAgency #ScalingBusiness #LifeScienceMarketing #BiotechInnovation #HealthcareEntrepreneur #PharmaDigitalMarketing #DavidOrmesher #HarshThakkar For transcripts, check out the podcast website - www.lifesciencespod.com…

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Could Worms REALLY Be the Key to Curing Autoimmune Diseases? 29:08

منذ عام واحد29:08

29:08

In this episode, we dive deep into a fascinating topic worm-derived therapeutics with our special guest Andrea, the founder and CEO of Holoclara. Did you know that autoimmune and allergic diseases were rare before the 1900s? What changed? Andrea shares groundbreaking insights into how worms, which have lived inside humans for millions of years, secrete molecules that could balance our immune system and help us tackle these diseases. From her early research days at Caltech to founding Holoclara, Andrea walks us through her journey, including: Chapters: 00:00 - The History of Autoimmune Diseases 01:24 - Why Watch This Video? 02:36 - Andrea’s Research Background 05:49 - The Turning Point: Entrepreneurship and Therapeutics 09:02 - Worms and Human Health: The Therapeutic Connection 11:32 - Worm Communication and Therapeutics 15:24 - The Industrial Revolution and Autoimmune Diseases 19:33 - How Worm-Derived Therapeutics Work 21:33 - Overcoming Challenges in Biotech 24:21 - The Future of Worm-Derived Therapeutics 25:48 - Studying Different Worm Species 26:57 - Life Outside Research 29:29 - Final Takeaway: Embracing Feedback and Opportunity Andrea also discusses the personal and scientific breakthroughs that led her to create Holoclara, a company dedicated to harnessing worm-derived molecules for modern medical solutions. Learn how roundworms evolved to produce tools that harmonize our immune system, and how these ancient organisms may hold the key to treating modern diseases. If you're intrigued by this incredible scientific journey and its implications for health, don't miss this episode! 🔗 Learn more about Holoclara: https://www.holoclara.com/ Linkedin: Andrea Choe, Co-Founder and CEO Holoclara https://www.linkedin.com/in/andreachoe/ Company page: https://www.linkedin.com/company/holoclara-inc/ - Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 💬 Let us know in the comments: Did you know worms could be this powerful? 👍 Don't forget to hit Like and Subscribe for more fascinating interviews with leaders in life sciences! #WormTherapeutics #AutoimmuneDiseases #HealthInnovation #BiotechBreakthrough #Holoclara #Immunology #MedicalResearch #LifeSciences #BiotechEntrepreneur #ImmuneSystemHealth #AllergyTreatment #RoundwormResearch #Therapeutics #HealthScience #ScientificDiscovery #MedicalInnovation #BiotechStartup #ImmuneBalance #WormDerivedMedicine For transcripts, check out the podcast website - www.lifesciencespod.com…

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How Amprion’s Test is Changing ALS, Dementia, and Parkinson’s Disease Diagnosis 37:18

منذ عام واحد37:18

37:18

Learn how misfolded proteins trigger cascading effects in the brain, leading to these devastating conditions, and how early detection can change the trajectory of treatment. Whether you’re curious about ALS, Parkinson’s, Dementia, or the role of molecular diagnostics. In this insightful episode, we dive deep into the world of neurodegenerative diseases, focusing on conditions like ALS, Parkinson's disease, Alzheimer's, and Dementia. Our guest, Russ Lebovitz, co-founder of Amprion, explains their groundbreaking work in detecting misfolded proteins, the primary culprits behind these diseases. From early diagnosis to understanding the role of technology and AI in healthcare, we explore how Amprion’s revolutionary diagnostic tools are shaping the future of brain health. Chapters: 00:00 - Introduction to the episode 00:13 - Amprion's unique approach to neurodegenerative diseases 00:40 - Misfolded proteins as the root cause 01:25 - Background of the guest, Russ Lebovitz 02:56 - Amprion's elevator pitch and core focus 03:59 - How Amprion detects misfolded proteins 05:57 - Misfolded proteins and their role in diseases 07:45 - The amplification process used by Amprion 09:27 - The causes of protein misfolding 12:29 - How Amprion's test works 14:05 - Early diagnosis through amplification 17:27 - Availability and expansion of Amprion's technology worldwide 21:03 - The role of AI in diagnosing neurodegenerative diseases 23:47 - Challenges in integrating AI into healthcare 27:17 - Predictions for future breakthroughs 32:35 - Collaboration between diagnostic tools, AI, and drug development 36:23 - Conclusion and closing remarks 🔗 Connect with Russ - Amprion website: (https://www.ampriondx.com) - Learn more about misfolded proteins and their role in brain diseases: (https://www.ampriondx.com/science) - Subscribe to our podcast for more insights on life sciences: 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr Don't forget to like and subscribe for more episodes on brain health, neurodegenerative diseases, and the future of healthcare technology! #NeurodegenerativeDiseases #ALS #ParkinsonsDisease #Dementia #BrainHealth #AlzheimersDisease #MisfoldedProteins #EarlyDiagnosis #MolecularDiagnostics #HealthcareAI #LifeSciences #BrainResearch #Amprion For transcripts, check out the podcast website - www.lifesciencespod.com…

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How Generative AI Finds Cures for Rare Diseases Faster 37:57

منذ عام واحد37:57

37:57

Welcome to episode 063 of Life Sciences 360. We dive deep into the groundbreaking role of AI in healthcare and life sciences with Shweta from Google Cloud. Learn how AI is accelerating drug discovery, enhancing patient care, and revolutionizing rare disease research. If you're passionate about the intersection of technology and health, this is a must-watch conversation! 🔗 Connect with Shweta on LinkedIn: https://www.linkedin.com/in/shwetasingh01/ 📍 Explore more about Google Cloud: (https://cloud.google.com) Chapters: 00:00 Introduction 00:01 Using Generative AI for Drug Discovery and Molecular Structures 00:11 Synthetic Images from Histological Data for Rare Diseases 00:20 Bayer's AI for Regulatory Dossiers 00:38 Categories of AI Perspectives in Healthcare 01:00 Shweta’s AI Journey & Joining Google Cloud 02:01 Methodical Approach to AI in Healthcare 02:43 AI for Rare Diseases & Accelerating Drug Research 05:01 First Steps for Companies Embracing AI 06:51 Real-World AI Use Cases: Ginkgo Bioworks & Bayer 10:32 Potential Future Frameworks for AI in Regulatory Submissions 13:52 Challenges of Rare Diseases & AI Solutions 16:05 AI's Role in Accelerating Research & Repurposing Drugs 18:10 Broader Applications of AI in Life Sciences Beyond Rare Diseases 19:22 AI for Drafting Clinical Trials & Patents 21:27 Addressing Concerns of AI in Healthcare: Ethics, Safety, and Bias 24:46 Human-in-the-Loop: The Key to Safe AI Use in Medicine 30:39 The Future of AI in Healthcare: Democratizing Access & Proactive Care 37:06 Outro & How to Connect with Shweta --- Links: *Harsh Thakkar LinkedIn ( https://www.linkedin.com/in/harshvthakkar/ ) *Listen to this episode on the go! 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 👍 Like this video if you enjoy diving deep into the latest healthcare trends. 💬 Comment below any questions you have. Have you implemented this into your operations yet? 🔔 Subscribe to our channel @lifesciences360 for more expert interviews about the rapidly evolving world of life sciences. 📲 Follow us on social media to keep up with the latest news and discussions in the biotech and pharmaceutical sectors. Thank you for watching and supporting our channel! #AIinHealthcare #LifeSciences #DrugDiscovery #GenerativeAI #ArtificialIntelligence #HealthcareInnovation #RareDiseases #AIMedicalResearch #PharmaTech #HealthcareAI #PatientCare #GoogleCloud #AIDrugDiscovery #TechInHealthcare #HealthTech #FutureOfHealthcare #MedicalAI #Biotech #DigitalHealth For transcripts, check out the podcast website - www.lifesciencespod.com…

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3 Steps to Avoid Burnout and Thrive in Biopharma, from a Global Expert 35:57

منذ عام واحد35:57

35:57

Welcome to episode 062 of Life Sciences 360. In this episode, we dive into an engaging conversation with Tom, a seasoned consultant, on how to recognize the early signs of burnout, foster a healthy and innovative work environment, and implement agility in regulated industries. Tom shares practical strategies for leaders and consultants alike to maintain performance without compromising mental well-being. Whether you're a business leader, consultant, or anyone looking to improve work-life balance, this video is packed with actionable advice! Chapters: 00:00 – Introduction 00:34 – Life as a Consultant: What It’s Really Like 01:00 – Burnout in Consulting vs. 9-to-5 Jobs 02:06 – Recognizing Early Signs of Burnout 03:56 – Overpromising and Work-Life Balance 04:31 – 3 Key Strategies to Prevent Burnout 05:52 – Managing Priorities and Influencing Decisions 09:55 – The Sandbox Approach to Innovation 12:02 – Innovation in Regulated Industries 14:30 – Encouraging Employee Experimentation 17:39 – Real-World Examples of Innovation Success 18:20 – Leadership Qualities That Promote Innovation 21:50 – Systems for Capturing and Reviewing Ideas 26:03 – Challenges of Implementing Agile in Regulated Industries 29:00 – Countering Opposition to Agile 33:01 – The Best Part of Consulting: Tom’s Take 34:48 – How to Connect with Tom 35:17 – Final Thoughts on Preventing Burnout Connect with Tom: LinkedIn: https://www.linkedin.com/in/tom-siebeneicher/ Spotify: https://open.spotify.com/episode/0aXLVMPZtFh79TKle9aN9y?si=4Xswz8zGTeKnkkogqB0BTg YouTube: https://www.youtube.com/playlist?list=PL3RKCnY-ES1kNaNP7WnQ37uiweOEbjB7O Links: *Harsh Thakkar LinkedIn ( https://www.linkedin.com/in/harshvthakkar/ ) *Listen to this episode on the go! 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 👍 Like this video if you enjoy diving deep into the latest healthcare trends. 💬 Comment below any questions you have. Have you implemented this into your operations yet? 🔔 Subscribe to our channel @lifesciences360 for more expert interviews about the rapidly evolving world of life sciences. 📲 Follow us on social media to keep up with the latest news and discussions in the biotech and pharmaceutical sectors. Thank you for watching and supporting our channel! #BurnoutPrevention #LeadershipTips #ConsultingLife #AgileMethodology #InnovationInBusiness #PreventBurnout #WorkLifeBalance For transcripts, check out the podcast website - www.lifesciencespod.com…

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How Samsung Biologics Achieved 16 Top Pharma Partnerships as a CDMO 43:15

منذ عام واحد43:15

43:15

Welcome to episode 061 of Life Sciences 360. In this episode of Life Sciences 360, host Harsh Thakkar sits down with Kevin Sharp, Senior Vice President and Head of Global Sales at Samsung Biologics. They dive deep into the evolving CDMO industry, the importance of agility, innovation, and the strategic growth pillars that are driving success at Samsung Biologics. Kevin shares his journey from government roles to life sciences, discusses the rapid advancements in ADCs, and explores how emerging technologies like AI are reshaping the industry. Chapters: 00:00 - Introduction 00:02 - Overcoming Roadblocks in the Industry 00:10 - Flexibility and Agility in Implementation 00:18 - Innovating Through Challenges 00:24 - The Mission of Life Sciences and Pharma 00:52 - The Speed Factor in Pharma Development 01:26 - Introduction to Kevin Sharp and Samsung Biologics 02:00 - Kevin Sharp's Career Journey to Life Sciences 03:29 - Transition from Pharma to CDMO Space 05:29 - The Rapid Growth of the CDMO Industry 07:14 - Key Challenges in Transitioning to a CDMO Role 09:22 - The Boom of CDMOs and Their Impact 11:32 - Regulatory Challenges and CDMO Expertise 13:48 - Strategic Partnerships with Top Pharma Companies 15:59 - The Importance of Diversification and Capability Growth 18:25 - Building Long-Term Partnerships with CDMOs 22:04 - Adapting to Roadblocks with Agility 23:59 - ADC Market Insights and Samsung Biologics’ Strategy 28:24 - The Future of Life Sciences: New Modalities and Technologies 30:27 - Leveraging Emerging Technologies like AI in CDMOs 34:52 - Leadership and Operational Excellence in Life Sciences 39:20 - Working at Samsung Biologics 41:17 - Final Thoughts and How to Connect with Kevin Sharp Connect with Kevin Sharp: Kevin's LinkedIn: (https://www.linkedin.com/in/kevinsharp) Samsung Biologics: (https://www.samsungbiologics.com/) Don’t forget to like, share, and subscribe for more insightful conversations on achieving success in life sciences and beyond! --- Links: *Harsh Thakkar LinkedIn ( https://www.linkedin.com/in/harshvthakkar/ ) *Listen to this episode on the go! 🍎Apple podcast: https://apple.co/3RXPoS1 🟩 Spotify podcast: https://spoti.fi/3EbDZbr 👍 Like this video if you enjoy diving deep into the latest healthcare trends. 💬 Comment below any questions you have. Have you implemented this into your operations yet? 🔔 Subscribe to our channel @lifesciences360 for more expert interviews about the rapidly evolving world of life sciences. 📲 Follow us on social media to keep up with the latest news and discussions in the biotech and pharmaceutical sectors. Thank you for watching and supporting our channel! #LifeSciences #Pharma #CDMO #Biotech #SamsungBiologics #Innovation #Leadership #AIinPharma #Healthcare #PharmaceuticalIndustry For transcripts, check out the podcast website - www.lifesciencespod.com…

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