Laboraverum News, 2024-09-25: drugs and placebos might have a common mechanism of action
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Researchers modelled chronic neuropathic pain in mice. The mice were injected anaesthetic drugs every time they entered a box with a peculiar colour scheme. When the injections of the drug stopped, the mice continued to experience pain relief when they were in the box. The effect persisted. However, the key cluster of neurons in the central amygdala that “turn off” pain when activated by anesthesia, did not activate in this case, so, it was a true placebo effect.
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