Writer/producer Sam Pasternack (@sampasternack) returns to the podcast to talk with Matt, Andy and Jesse about awful bar trivia, Sam's new book "Walker," the history of pedestrianism, Land's End to John o' Groats, Andy's Burning Man updates, the dilemma of trombone utility and using massive python meals to help develop new human heart medicines.…

Mystery Science Theater alum, comedian and author Frank Conniff (@FrankConniff) joins the crew to talk about his new audiobook Dark Apnea. Plus horoscope doubts! Carl Sagan predicting the future! And where dinosaur killing asteroids came from! In the patreon bonus ep we talk about saving the banana from extinction. Sign up here!…

Comedian Mark Cohen (@mark_coco_cohen) joins Jesse, Andy and Matt to discuss the two aging bursts humans experience, restoring Tonka trucks, weaning crocodiles off of cane toads, Mark's video game creations, using slime mold to help map dark matter, and stock photo artists who play Lawn Mowing Simulator. and Mark's possible record-breaking stint at…

Neuroscientist-turned-comedian Isak Allen (@isakallen) joins Matt, Jesse and Andy to talk about smashing flies, using fMRI to study brain activity as it relates to music and comedy, tonal languages, the Dong Song, Neuralink, dystopian futures and Isak's new Dry Bar special Culturally Unavailable.

We've got just the prescription for everyone out there with Olympic fever: A re-release of a 2013 episode in which Matt and Andy interview David Epstein, a Sports Illustrated journalist and the author of the outstanding book The Sports Gene, along with college basketball player-turned-comedian Paul Morrissey, to discuss the field of sports genetics…

Comedy legend Cathy Ladman (@cathyladman1) joins Jesse, Andy and Matt to talk about creepy Foundation for a Better Life billboards, cancer battles, 1970s acid, the CrowdStrike software crash, how propofol tips your brain into chaos, the merits of comedy classes, Brazilian cocaine sharks and Cathy's September 7th Vegas show.…

Producer David Brown joins Jesse, Matt and Andy to talk about creating entertaining science programming, the new Peacock show The Hungry Games: Alaska's Big Bear Challenge that David produced, Rhys Darby narrated and Matt and Andy worked on, the Emmy-winning pop-science show Could You Survive The Movies?, Andy's Top Gun cameo, Fat Bear Week, Goro's…

Comedian Todd Barry (@toddbarry) joins Matt, Andy and Jesse to talk about his new special Domestic Shorthair, an FDA ban of a citrus soda ingredient, ginger ale vs. ginger beer, the quackery of Dr. Idz, new images of an asteroid that just whizzed by Earth, Jesse's air force base food poisoning story, whether toxoplasmosis causes crazy cat lady synd…

Comedian Sid Singh (@mrsidsingh) joins Andy, Jesse and Matt to talk about being a Brexit and Biden bellwether, Mozart the millenial, weird tunings, 432 Hz bullshit, old-ass Washington cherries, SPATS updates, a clever way to curb rhino horn poaching, meat rice, debunking Novi's etymology and ant surgeons.…

Writer/podcaster Jordan Morris (@Jordan_Morris) returns to the show to talk with Matt, Jesse and Andy about his upcoming graphic novel Youth Group, the YA genre, hawk tuah, breakdancing in the Olympics, elephants calling each other by name, wartime magicians, GPT-4 passing the Turing Test, using AI to cancel customer anger, a new stab at AI alignme…

Matt and Andy host a live installment of the podcast from To 29 and Beyond in Twentynine Palms featuring guests Bobcat Goldthwait, Rhys Darby, Dr. Farah Alibay and Natalia Reagan, digging into topics including indoor rocketry, opening for Nirvana, projectile bibles, the Cryptid Factor podcast, Bobcat's Bigfoot movie, 10 Million Dollar Bigfoot Bount…

Comedian, quizzer, doctor, chaser and now author Paul Sinha (@paulybengali) joins Jesse, Andy and Matt about his new memoir One Sinha Lifetime, training for quiz shows, underperforming on Taskmaster, Paul’s Parkinson’s diagnosis, how he transitioned from medicine to comedy, being outed decades after coming out, this weekend’s To 29 and Beyond, the …

Comedian, actor and host of The Tomorrow Show Ron Lynch (@ronlynch1) checks in with Matt, Jesse and Andy to talk about the groundbreaking show Home Movies, Ron's geology degree, microplastics in your balls, Terrence Howard's magnificent bullshit, reducing the carbon footprint of cement, using the Sun as a giant telescope and of course To 29 and Bey…

Comedian Omid Singh (@omid_singh) joins Jesse, Andy and Matt to talk about Omid's Lil Special, the recent additions to the To 29 and Beyond lineup, including Moshe Kasher and Natasha Leggero's Endless Honeymoon podcast and Rhys Darby, southern indifference to northern lights, Omid's dream song, Dubai construction projects, The Line in Saudi Arabia,…

Comedian Shane Mauss (@shane_mauss) returns to the podcast in the midst of his A Better Trip tour to talk with Matt and Andy about having his van broken into, his new line of plant activated products, the connection between Amanita muscaria mushrooms and Mario and Santa, the trendiness of ketamine, a psychedelic toad venom that may have therapeutic…

Comedian Sierra Katow (@sierrakatow) joins Jesse, Andy and Matt to talk about her new standup special Funt, the upcoming appearance on Roots of Comedy with Jesus Trejo, the underrated Earth to Ned, Sierra's computer science background and childhood obsession with Neopets, Andy's head-scratching interaction with Anthropic's Claude AI, deadly pathoge…

Comedian Bec Hill (@bechillcomedian) joins Andy, Matt and Jesse to talk about What3Words, Bec sneaking dicks into things, a surprise from decades-old cans of salmon, ghost particles, a possible Stonehenge moon connection, ancient Stonehenge feasts, Willy's LA Chocolate Experience, A Problem Squared, Enemy In Paris and of course To 29 and Beyond, co…