أفضل بودكاسات Genotype (2024)

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Genotype - Test Of Time - Deeper Sessions (DS) 5:50

1d ago5:50

5:50

Buy : https://genotypejjungle.bandcamp.com/album/genotype-test-of-time-deeper-sessions-ds1. Test Of Time2. Schedule3. Hover Time4. Long Lasting5. Edit CrazySocial Links :Soundcloud : https://soundcloud.com/genotype-justj...Bandcamphttp://genotypejjungle.bandcamp.com/Instagramhttp://Instagram.com/genotypejjungleGenotype & Just Jungle Official Group …

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Zika Virus as a Treatment for Brain Cancer: A Systematic Review 3:28

15h ago3:28

3:28

BUFFALO, NY- October 9, 2024 – A new #review was #published in Oncotarget's Volume 15 on September 30, 2024, entitled, “Zika virus and brain cancer: Can Zika be an effective treatment for brain cancer? A systematic review.”As highlighted in the introduction of this review, many studies have identified oncolytic viruses as a promising new class of t…

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Lessons from ACDC-RP Trial: Designing Neoadjuvant Therapy Trials for Prostatectomy 3:07

2d ago3:07

3:07

Oncotarget #published this #editorial on September 30, 2024, in Volume 15, entitled “Lessons from the ACDC-RP trial: Clinical trial design for radical prostatectomy neoadjuvant therapy trials” by Rashid K. Sayyid and Neil E. Fleshner from the Division of Urologic Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Can…

1
Mastermind DNB - One Night Stand EP 6:24

5d ago6:24

6:24

Buy : Tracks : 1. One Night Stand2. Elevated3. Eyes4. Moment Of Truth5. Give To MeSocial Links :Soundcloud : https://soundcloud.com/genotype-justj...Bandcamphttp://genotypejjungle.bandcamp.com/Instagramhttp://Instagram.com/genotypejjungleGenotype & Just Jungle Official Group Pagehttps://www.facebook.com/groups/11496...Twitterhttp://twitter.com/geno…

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Genotype & Jubzkilla - Old Oak EP (Just Jungle Remixes) 5:10

5d ago5:10

5:10

Buy : https://genotypejjungle.bandcamp.com/album/genotype-jubzkilla-old-oak-ep-just-jungle-remixesTracks : 1. Angostura RMX2. Old Oak RMX3. Metaphysical RMX4. Dulcet RMX5. Mellifluous RMXSocial Links :Soundcloud : https://www.soundcloud.com/genotype-justjungle-1Bandcamphttp://genotypejjungle.bandcamp.com/Instagramhttp://Instagram.com/genotypejjungl…

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TWiEVO 106: What's old immunity is new again 1:28:49

9d ago1:28:49

1:28:49

Nels and Vincent explain how homology searches of anti-phage systems in eukaryotic genomes can be used to discover proteins of the human immune system. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiEVO Links for this episode Join the MicrobeTV Discord server Human antiviral effectors from…

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TWiEVO 105: Not every rose has its thorn 1:31:09

9d ago1:31:09

1:31:09

Nels and Vincent look at how plant prickles, sharp epidermal projections that provide defense from predators and other advantages, arose by convergent evolution, the emergence of analogous traits in distantly related species. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWi…

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Genotype & Jubzkilla - Old Oak EP 5:53

27d ago5:53

5:53

Buy : https://genotypejjungle.bandcamp.com/album/genotype-jubzkilla-old-oak-epTracks :1. Old Oak2. Angostora3. Dulcet4. Metaphysical5. MellifluousSocial Links :Soundcloud : https://soundcloud.com/genotype-justjungle-1Bandcamphttp://genotypejjungle.bandcamp.com/Twitterhttp://twitter.com/genotypedbInstagramhttp://instagram.com/genotypejjungleJustin R…

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Heavy Cargo EP - Just Jungle, Genotype, Mastermind DNB - G Lab 5:16

1M ago5:16

5:16

Buy : https://genotypejjungle.bandcamp.com/album/heavy-cargo-epTracks :1. Just Jungle - Sewagehttps://genotypejjungle.bandcamp.com/track/sewage2. Just Jungle - Heavy Cargohttps://genotypejjungle.bandcamp.com/track/heavy-cargo3. Mastermind DNB - Closerhttps://genotypejjungle.bandcamp.com/track/closer4. Genotype - Axishttps://genotypejjungle.bandcamp…

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Key Roles of MIF, DDT, and CD74 in Melanoma Prognosis and Therapy 4:02

1M ago4:02

4:02

Macrophage Migration Inhibitory Factor (MIF) and its homolog D-dopachrome Tautomerase (DDT) have been implicated as drivers of tumor progression in various cancers. Recent evidence suggests that MIF could be a therapeutic target in immune checkpoint inhibition (ICI) resistant melanomas; however, clinical evidence for MIF, and particularly for DDT, …

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miR-10b Inhibition: A Strategy for Treating Metastatic Breast Cancer 2:41

1M ago2:41

2:41

BUFFALO, NY- August 28, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on August 26, 2024, entitled, “Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties.”As stated within the Abstract of the paper, despite advances in breast cancer screening and treatment, the prognosis for metastatic…

1
Artificial Intelligence: Revolutionizing Precision Oncology 2:21

1M ago2:21

2:21

BUFFALO, NY- August 27, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on August 26, 2024, entitled, “Artificial intelligence: A transformative tool in precision oncology.”Artificial intelligence (AI) is revolutionizing society and healthcare, opening new possibilities for precision medicine. In oncology, immunotherapy (IO) has si…

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Genotype Matters: Tailored Screening for Germline CHEK2 Variants 2:45

1M ago2:45

2:45

BUFFALO, NY- August 26, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on July 10, 2024, entitled, “Genotype matters: Personalized screening recommendations for germline CHEK2 variants.”Recognized as a moderate-risk gene, CHEK2—responsible for encoding the CHK2 protein, which plays a crucial role in the repair of DNA double-strand…

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Disrupting NKG2A:HLA-E Interactions for Enhanced Anti-Cancer Immunity 2:39

2M ago2:39

2:39

BUFFALO, NY- August 21, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on July 17, 2024, entitled, “Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity.”Two studies using CRISPR screens in cancer cells identified HLA-E as a critical negative regulator of NK cell interactions with cancer cells. Consiste…

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Role of the Gut Barrier in Colorectal Cancer Treatment 2:42

2M ago2:42

2:42

BUFFALO, NY- August 19, 2024 – A new #review was #published in Oncotarget's Volume 15 on August 14, 2024, entitled, “The gut barrier as a gatekeeper in colorectal cancer treatment.”Colorectal cancer (CRC) is highly prevalent and a major cause of cancer-related deaths worldwide. The primary curative treatment for CRC is surgical resection of the aff…

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Nanobody Inhibits Metastasis of Breast Tumor Cells to Lung in Mice 2:53

2M ago2:53

2:53

BUFFALO, NY- August 15, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on August 14, 2024, entitled, “A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice.”The vacuolar H+-ATPase (V-ATPase) is an ATP-dependent proton pump that functions to control the pH of intracellular …

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Response of BRAF-Mutated Spindle Cell Sarcoma to BRAF/MEK Inhibitors 2:48

2M ago2:48

2:48

BUFFALO, NY- August 14, 2024 – A new #casereport was #published in Oncotarget's Volume 15 on July 17, 2024, entitled, “Rapid but nondurable response of a BRAF exon 15 double-mutated spindle cell sarcoma to a combination of BRAF and MEK inhibitors.”As noted in the introduction of the Abstract, the BRAF V600E substitution predicts a cancer's sensitiv…

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New Directions in Targeting the Multifaceted BRAF in Cancer 2:28

2M ago2:28

2:28

BUFFALO, NY- August 12, 2024 – A new research perspective was published in Oncotarget's Volume 15 on July 16, 2024, entitled, “Targeting the multifaceted BRAF in cancer: New directions.”In cancer patients, BRAF-targeting precision therapeutics are effective against Class I BRAF alterations (p.V600 hotspot mutations) in tumors such as melanoma, thyr…

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Combining Regorafenib and TAS102 to Target Gastrointestinal Cancers and Overcome Cancer Stemness 4:01

2M ago4:01

4:01

In this research paper, researchers demonstrate a promising new treatment option for refractory metastatic gastrointestinal cancers using a combination of two FDA-approved drugs.Researchers Jun Zhang, Lanlan Zhou, Shuai Zhao, and Wafik S. El-Deiry from Fox Chase Cancer Center and Brown University explore the potential of combining TAS102 (triflurid…

1
TCR CDR3s and Renalase-1 Linked to Increased Melanoma Survival 2:31

2M ago2:31

2:31

BUFFALO, NY- August 8, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on August 5, 2024, entitled, “Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival.”As mentioned in the Abstract of this study, overexpression of the secretory protein renalase-1 negati…

1
Dealing with Runaway Metastatic Disease 1:59

2M ago1:59

1:59

BUFFALO, NY - August 7, 2024 – A new #editorial paper was #published in Oncotarget's Volume 15 on July 12, 2024, entitled, “How to deal with runaway metastatic disease?”In this new editorial, Justine Paris and Guilhem Bousquet from Université Paris Cité, Université Sorbonne Paris Nord, and APHP, Hôpital Avicenne, Oncologie médical, discussed how th…

1
INT-1B3 miR-193a-3p Mimic Boosts T Cell Immunity and Induces Tumor Cell Death 2:34

2M ago2:34

2:34

BUFFALO, NY- August 5, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on July 12, 2024, entitled, “INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death.”In this study, resear…

1
Just Jungle - Taking It Back EP 2 - G Skool 4:16

2M ago4:16

4:16

Buy : https://genotypejjungle.bandcamp.com/album/just-jungle-taking-it-back-ep-2-g-skoolTracks : 1. Bredrin From Space2. Riddem Emphasis3. Squat Rave4. Ear Sharp5. HumidSocial Links :Soundcloud : https://www.soundcloud.com/genotype-justjungle-1Bandcamphttp://genotypejjungle.bandcamp.com/Instagramhttp://Instagram.com/genotypejjungleGenotype & Just J…

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TWiEVO 104: Wooly mammoth prosciutto 1:17:37

2M ago1:17:37

1:17:37

Nels and Vincent discuss the genome sequence of an ancient wooly mammoth, which shows that the three-dimensional architecture of the DNA can persist after 50,000 years. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode Join the MicrobeTV Discord ser…

1
Prognostic and Therapeutic Insights Into MIF, DDT, and CD74 in Melanoma 3:32

3M ago3:32

3:32

BUFFALO, NY- July 26, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on July 19, 2024, entitled, “Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma.”Macrophage Migration Inhibitory Factor (MIF) and its homolog D-dopachrome Tautomerase (DDT) have been implicated as drivers of tumor progression across a va…

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Novel Triple-Drug Combination to Fight Pancreatic Cancer 8:10

3M ago8:10

8:10

In the ever-evolving quest for effective cancer treatments, researchers are continuously exploring innovative combinatorial approaches that exploit the vulnerabilities of malignant cells. In a new study, researchers Benigno C. Valdez, Apostolia M. Tsimberidou, Bin Yuan, Yago Nieto, Mehmet A. Baysal, Abhijit Chakraborty, Clark R. Andersen, and Borje…

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Prevalence and Impact of the KIT M541L Variant in Patients with Mastocytosis 2:54

3M ago2:54

2:54

BUFFALO, NY- July 24, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on July 22, 2024, entitled, “Prevalence and impact of the KIT M541L variant in patients with mastocytosis.”Activating mutations in KIT, particularly D816V, have been associated with mastocytosis. Additionally, expression of heterozygous KIT M541L has been pr…

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Oncotarget Welcomes New Editorial Board Members 1:40

3M ago1:40

1:40

BUFFALO, NY - July 22, 2024 – Oncotarget proudly welcomes new members to our esteemed Editorial Board, including our new Co-Editor-in-Chief, Dr. Wafik S. El-Deiry. Joining Dr. El-Deiry on Oncotarget’s Editorial Board are Dr. Trever Bivona, Dr. Phillip Buckhaults, Dr. Fred Bunz, Dr. Jonathan Chernoff, Dr. Stephen G. Chun, Dr. Nathan Dolloff, Dr. Pei…

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Efficacy of Pembrolizumab with sEphB4-HSA in HPV-negative EphrinB2-positive HNSCC 3:21

3M ago3:21

3:21

BUFFALO, NY- July 22, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on July 10, 2024, entitled, “Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma.”Patients with relapsed or metastatic head and neck squamous cell carcinoma (HNSCC) after …

1
DDX41’s Unique Contribution to Myeloid Leukemogenesis 2:35

3M ago2:35

2:35

BUFFALO, NY- July 19, 2024 – A new #editorial paper was #published in Oncotarget's Volume 15 on July 2, 2024, entitled, “DDX41 and its unique contribution to myeloid leukemogenesis.”In this new editorial, researcher Hirotaka Matsui from the National Cancer Center Hospital in Tokyo, Japan, and Kumamoto University discusses myeloid neoplasms. Until t…

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Using Early On-treatment ctDNA Measurements as Response Assessment in mCRPC 2:34

3M ago2:34

2:34

BUFFALO, NY- July 17, 2024 – A new #editorial paper was #published in Oncotarget's Volume 15 on July 2, 2024, entitled, “Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer.”In this new editorial, researchers S.H. Tolmeijer, E. Boerrigter, N.P. Van Erp, and Niven Mehr…

1
HER2-low and HER2-zero in Breast Cancer Between Prognosis, Prediction and Entity 2:41

3M ago2:41

2:41

BUFFALO, NY- July 16, 2024 – A new #editorial paper was #published in Oncotarget's Volume 15 on June 20, 2024, entitled, “HER2-low and HER2-zero in breast cancer between prognosis, prediction and entity.”In this new editorial, researchers Marcus Schmidt, Hans-Anton Lehr, and Katrin Almstedt from the University Medical Center of Johannes Gutenberg U…

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Comparison of FDG-PET/CT and CT for Treatment Evaluation of Patients With Unresectable Mesothelioma 4:12

3M ago4:12

4:12

BUFFALO, NY- July 15, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on June 20, 2024, entitled, “Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma.”Malignant pleural mesothelio…

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AI for Improved PET/CT Attenuation Correction in Prostate Cancer Imaging 5:51

3M ago5:51

5:51

Positron Emission Tomography (PET) combined with Computed Tomography (CT) is a powerful imaging modality used in oncology for diagnosis, staging, and treatment monitoring. However, one limitation of PET/CT is the need for accurate attenuation correction (AC) to account for tissue density variations. Traditionally, low-dose CT scans are used for AC,…

1
Targeting ABC Transporters in PDAC – Past, Present, or Future? 3:00

3M ago3:00

3:00

BUFFALO, NY- July 10, 2024 – A new #editorial paper was #published in Oncotarget's Volume 15 on June 20, 2024, entitled, “Targeting ABC transporters in PDAC – past, present, or future?”In this new editorial, Cecilia Bergonzini, Elisa Giovannetti and Erik H.J. Danen from Leiden University discuss targeting ABC transporters in pancreatic ductal carci…

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TWiEVO 103: Change the world by duplicating yourself 1:38:49

3M ago1:38:49

1:38:49

Nels and Vincent explore a direct experimental test of Ohno’s Hypothesis, which states that gene duplication can help genes tolerate new mutations and thus facilitates the evolution of new phenotypes. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episod…

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Regorafenib Synergizes With TAS102 Against Multiple Gastrointestinal Cancers 3:25

3M ago3:25

3:25

BUFFALO, NY- July 8, 2024 – A new research paper was published in Oncotarget's Volume 15 on July 2, 2024, entitled, “Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status.”Single-agent TAS1…

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Editorial: Genomics Has More to Reveal 2:33

3M ago2:33

2:33

BUFFALO, NY- July 2, 2024 – A new editorial paper was published in Oncotarget's Volume 15 on June 20, 2024, entitled, “Genomics has more to reveal.”In this new editorial, researchers Laurène Fenwarth and Nicolas Duployez from the University of Lille and CHU Lille discuss molecular and cytogenetic analyses that are now used to identify mutations and…

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Starving Cancer Cells to Enhance DNA Damage and Immunotherapy Response 2:55

4M ago2:55

2:55

BUFFALO, NY- June 26, 2024 – A new research perspective was published in Oncotarget's Volume 15 on June 20, 2024, entitled, “Starving cancer cells to enhance DNA damage and immunotherapy response.”Prostate cancer (PCa) poses significant challenges in treatment, particularly when it progresses to a metastatic, castrate-resistant state. Conventional …

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Leveraging Gold Nanostars for Precision Laser Interstitial Thermal Therapy 2:42

4M ago2:42

2:42

BUFFALO, NY- June 24, 2024 – A new editorial paper was published in Oncotarget's Volume 15 on June 14, 2024, entitled, “Leveraging gold nanostars for precision laser interstitial thermal therapy.”In this new editorial, researchers Aden P. Haskell-Mendoza, Ethan S. Srinivasan, Tuan Vo-Dinh and Peter E. Fecci from Duke University discuss laser inters…

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Impact of Dual Immunotherapies Before Surgery in HR+/HER2-negative Breast Cancer 8:47

4M ago8:47

8:47

Breast cancer immunotherapy has shown promise, but its clinical efficacy remains limited, especially for hormone receptor positive (HR+)/HER2-negative breast cancer. While immune checkpoint inhibitors combined with chemotherapy have benefitted some early-stage and metastatic triple-negative breast cancer patients, HR+/HER2-negative cases have seen …

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Assessment of CEA, CA-125, and CA19-9 as Adjuncts in Non-small Cell Lung Cancer Management 3:24

4M ago3:24

3:24

BUFFALO, NY- June 19, 2024 – A new research paper was published in Oncotarget's Volume 15 on June 13, 2024, entitled, “Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management.”Conventional tumor markers may serve as adjuncts in non-small cell lung cancer (NSCLC) management. In this new study, r…

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When Does a Melanoma Metastasize? Implications for Management 2:18

4M ago2:18

2:18

BUFFALO, NY- June 18, 2024 – A new #research perspective was #published in Oncotarget's Volume 15 on June 13, 2024, entitled, “When does a melanoma metastasize? Implications for management.”In this new perspective, researchers John F. Thompson and Gabrielle J. Williams from The University of Sydney, Royal Prince Alfred Hospital, and the University …

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Just Jungle - G Skool 27 5:19

4M ago5:19

5:19

Just Jungle - G Skool 27Buy : https://genotypejjungle.bandcamp.com/album/just-jungle-g-skool-27Tracks :1. Crisis2. Lockheed3. Moray4. Goosebumps5. Early ReflectionSocial Links :Soundcloud : https://www.soundcloud.com/genotype-justjungle-1Bandcamphttp://genotypejjungle.bandcamp.com/Instagramhttp://Instagram.com/genotypejjungleGenotype & Just Jungle …

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Impact Journals Sponsors 2024 Ride for Roswell 3:59

4M ago3:59

3:59

BUFFALO, NY- June 11, 2024 – The Ride for Roswell is one of the nation’s largest cycling events—hosted by Roswell Park Comprehensive Cancer Center—to raise awareness and funds for cancer research and patient care. This charity bike ride, based out of Buffalo, New York, has brought people together for 28 years to celebrate cancer survivors, pay trib…

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Dr. Blagosklonny’s Strategy: From Osimertinib to Preemptive Combinations 8:07

4M ago8:07

8:07

In the relentless battle against non-small cell lung cancer (NSCLC) driven by epidermal growth factor receptor (EGFR) mutations, the development of resistance has long been a formidable obstacle. Historically, first- and second-generation EGFR tyrosine kinase inhibitors (TKIs) like gefitinib, erlotinib, afatinib, and dacomitinib have faced a signif…

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