Personalised Medicine 2: first ya gotta understand the proteins

Understanding Childhood Cancer With Dr Geoff

Understanding Childhood Cancer With Dr Geoff

Player FM - Internet Radio Done Right

11 subscribers

تمت الإضافة منذ قبل nine عام

المحتوى المقدم من Dr Geoff, Dr Geoffey McCowage, and Senior Paediatric Oncologist. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرة بواسطة Dr Geoff, Dr Geoffey McCowage, and Senior Paediatric Oncologist أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.

Lipstick on the Rim

1
Amy Schumer & Brianne Howey on the Importance of Female Friendships, Navigating Hollywood's Double Standards, Sharing Their Birth Stories, and MORE 50:05

منذ 19 يومًا50:05

التشغيل لاحقا

قوائم

إعجاب

احب

50:05

This week, in what might be the funniest episode yet, Molly and Emese are joined by co-stars Amy Schumer and Brianne Howey. They get candid about motherhood, career evolution, and their new film, Kinda Pregnant —which unexpectedly led to Amy’s latest health discovery. Amy opens up about how public criticism led her to uncover her Cushing syndrome diagnosis, what it’s like to navigate comedy and Hollywood as a mom, and the importance of sharing birth stories without shame. Brianne shares how becoming a mother has shifted her perspective on work, how Ginny & Georgia ’s Georgia Miller compares to real-life parenting, and the power of female friendships in the industry. We also go behind the scenes of their new Netflix film, Kinda Pregnant —how Molly first got the script, why Amy and Brianne were drawn to the project, and what it means for women today. Plus, they reflect on their early career struggles, the moment they knew they “made it,” and how motherhood has reshaped their ambitions. From career highs to personal challenges, this episode is raw, funny, and packed with insights. Mentioned in the Episode: Kinda Pregnant Ginny & Georgia Meerkat 30 Rock Last Comic Standing Charlie Sheen Roast Inside Amy Schumer Amy Schumer on the Howard Stern Show Trainwreck Life & Beth Expecting Amy 45RPM Clothing Brand A Sony Music Entertainment production. Find more great podcasts from Sony Music Entertainment at sonymusic.com/podcasts and follow us at @sonypodcasts To bring your brand to life in this podcast, email podcastadsales@sonymusic.com Learn more about your ad choices. Visit podcastchoices.com/adchoices…

منذ 9 أعوام 17:14

MP3•منزل الحلقة

To understand all this DNA analysis business, first one needs to know a bit about proteins. Proteins basically do all the work in cells, and so DNA mutations interfere with protein structures.Serious geek alert! Link to Patreon

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81 حلقات

#Science #Childhood Cancer #Dr Geoff

Understanding Childhood Cancer With Dr Geoff

Personalised Medicine 2: first ya gotta understand the proteins

Understanding Childhood Cancer With Dr Geoff

11 subscribers

published منذ 9 أعوام

MP3•منزل الحلقة

Hosted on Acast. See acast.com/privacy for more information.

81 حلقات

#Science #Childhood Cancer #Dr Geoff

Minden epizód

Understanding Childhood Cancer With Dr Geoff

1
CAR T-cells, Interview with Dr Caroline Bateman 45:55

منذ 3 years45:55

45:55

CAR T-cell therapy is an exciting new treatment for acute leukaemia. In this episode, Dr Geoff interviews his colleague Dr Caroline Bateman about CAR T-cells and introducing the treatment option to her unit. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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"S" is for "Special" : Stage MS Neuroblastoma (also called Stage IVS, 4S) 24:26

منذ 4 years24:26

24:26

There is a special subtype of neuroblastoma seen in very young children, with spread of disease throughout the body, but which needs a very different approach to treatment compared to older children with metastatic disease. This episode explains the features of this stage MS neuroblastoma, the early problems, and the treatment used. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.…

Understanding Childhood Cancer With Dr Geoff

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Where did my child's immune system go? 44:44

منذ 4 years44:44

44:44

Childhood cancer treatment leads to severe impairment of the ability to fight infections. This episode explains what immune suppression means, what causes it, and the problems that result. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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Update re the future of rock and roll.... CAR T-cells 39:46

منذ 4 years39:46

39:46

A few years ago I described CAR T-cells, but they weren't available for routine use. I now update things, with the very important news about CAR T-cell therapy now becoming available. There is also an interview with Dr Caroline Bateman re this subject in another episode. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.…

Understanding Childhood Cancer With Dr Geoff

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Blood Cultures 22:13

منذ 4 years22:13

22:13

We take a lot of blood samples looking for infection in the bloodstream. This episode explains what blood cultures are all about. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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PRISM, Molecular Profiling, and Informed Consent 56:12

منذ 4 years56:12

56:12

A number of countries have research studies where childhood cancers are analysed in great detail, testing all the DNA in something called 'molecular profiling'. The national Australian study of this is called PRISM, and it is a very exciting project. This episode explains a molecular profiling project and covers issues of obtaining informed consent from parents and patients as well. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.…

Understanding Childhood Cancer With Dr Geoff

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The MEK inhibitors: trametinib and selumetinib 41:14

منذ 4 years41:14

41:14

The MEK inhibitors are a newer class of drug, and include trametinib, selumetinib and others. They have an important role in paediatric oncology, particularly in glioma treatment and in neurofibromatosis. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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The needle in the haystack: Minimal Residual Disease 42:05

منذ 4 years42:05

42:05

Sophisticated techniques can detect one cancer cell amongst a million normal cells. This episode describes these methods and how they are used in treatment. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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DIPG: to biopsy or not to biopsy 13:37

منذ 4 years13:37

13:37

For many years we didn't biopsy the tumour when the scans suggested that the tumour was a DIPG. This episode explains why that has changed, and the emerging role of biopsy. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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DIPG: what do these letters stand for? 19:55

منذ 8 years19:55

19:55

DIPG is a type of brain tumor which occurs in children. This episode explains what the letters mean. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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Chemotherapy 7: Ifosfamide 22:51

منذ 8 years22:51

22:51

Ifosfamide is another chemotherapy drug, used particularly in certain sarcomas and certain patients with leukaemia. This episode explains how it is given, and common and rare side effects. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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Why does my child need a heart test? Echo's and ECG's. 16:42

منذ 8 years16:42

16:42

We often need to evaluate heart function during chemotherapy. This episode explains what the tests are, and why we need to do them. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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Highlights of ASCO: Two transplants for neuroblastoma?? 30:12

منذ 9 years30:12

30:12

At the American Society of Clinical Oncology meeting in June 2016, a study was presented looking at using two autologous bone marrow transplants in neuroblastoma. The results were exciting.... Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

Understanding Childhood Cancer With Dr Geoff

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"A Selfless Act": my reading of an article on clinical trials in childhood cancer. 17:52

منذ 9 years17:52

17:52

In this episode I read out for you an article written by Dr Susan Cohn from the University of Chicago. Dr Cohn is an eminent paediatric oncologist, and a world expert on children's cancer trials, particularly in neuroblastoma. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.…

Understanding Childhood Cancer With Dr Geoff

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Residents, fellows, registrars; who are all these doctors? 31:49

منذ 9 years31:49

31:49

When families find themselves in a hospital, they meet all sorts of doctors with all sorts of titles, residents, interns, fellows, registrars. This episode explains who's who in the childhood cancer medical team. Link to Patreon Hosted on Acast. See acast.com/privacy for more information.

مرحبًا بك في مشغل أف ام!

يقوم برنامج مشغل أف أم بمسح الويب للحصول على بودكاست عالية الجودة لتستمتع بها الآن. إنه أفضل تطبيق بودكاست ويعمل على أجهزة اندرويد والأيفون والويب. قم بالتسجيل لمزامنة الاشتراكات عبر الأجهزة.