Early Development and The Dose Selection in the Immune-oncology

The Effective Statistician - in association with PSI

The Effective Statistician - in association with PSI

Player FM - Internet Radio Done Right

107 subscribers

Data Science

تمت الإضافة منذ قبل seven عام

المحتوى المقدم من Alexander Schacht and Benjamin Piske, biometricians, statisticians and leaders in the pharma industry, Alexander Schacht, Benjamin Piske, and Leaders in the pharma industry. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرة بواسطة Alexander Schacht and Benjamin Piske, biometricians, statisticians and leaders in the pharma industry, Alexander Schacht, Benjamin Piske, and Leaders in the pharma industry أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.

The So What from BCG

1
Re-Recruiting and Other New HR Strategies You Can’t Ignore 18:09

منذ 10 أيام18:09

التشغيل لاحقا

قوائم

إعجاب

احب

18:09

HR is no longer just about managing people—it’s about shaping the future of work. Jens Baier, BCG’s HR transformation expert, discusses how AI and shifting employee expectations are forcing companies to rethink talent strategies. From re-recruiting to upskilling employees, HR must adapt to a rapidly changing landscape. Learn More: Jens Baier: https://on.bcg.com/41ca7Gv BCG on People Strategy: https://on.bcg.com/3QtAjro Decoding Global Talent: https://on.bcg.com/4gUC4IT…

منذ عام واحد 21:59

AAC•منزل الحلقة

Interview with Teppo Huttunen

Key points:

Dose Selection Challenge
Limitations of 3+3 Design
BOIN Design
Backfilling
Efficacy vs. Safety
Statisticians’ Role
Practical Challenges
FDA Guidance
Cross-Functional Approach
Industry Trends
Cost & Timeline Estimation

Understanding dose selection in immune-oncology is crucial for developing safer and more effective treatments, and statisticians play a central role in driving these decisions.

In this episode, Teppo shares practical insights into overcoming the limitations of traditional methods and adopting more flexible approaches like the BOIN design.

If you want to stay ahead in oncology research and learn how to balance safety, efficacy, and practical challenges in dose optimization, this episode is a must-listen!

432 حلقات

#Natural Sciences #Statistics #Biostatistics #Pharmaceutical #Benjamin Piske #Alexander Schacht #Leaders in the pharma industry #Data Science #Science #Psy

The Effective Statistician - in association with PSI

Early Development and The Dose Selection in the Immune-oncology

The Effective Statistician - in association with PSI

107 subscribers

published منذ عام واحد

AAC•منزل الحلقة

Interview with Teppo Huttunen

Key points:

Dose Selection Challenge
Limitations of 3+3 Design
BOIN Design
Backfilling
Efficacy vs. Safety
Statisticians’ Role
Practical Challenges
FDA Guidance
Cross-Functional Approach
Industry Trends
Cost & Timeline Estimation

Understanding dose selection in immune-oncology is crucial for developing safer and more effective treatments, and statisticians play a central role in driving these decisions.

In this episode, Teppo shares practical insights into overcoming the limitations of traditional methods and adopting more flexible approaches like the BOIN design.

If you want to stay ahead in oncology research and learn how to balance safety, efficacy, and practical challenges in dose optimization, this episode is a must-listen!

432 حلقات

#Natural Sciences #Statistics #Biostatistics #Pharmaceutical #Benjamin Piske #Alexander Schacht #Leaders in the pharma industry #Data Science #Science #Psy

كل الحلقات

The Effective Statistician - in association with PSI

1
Building the Influence as a Statistician in a Clinical Trial Team 14:10

منذ 1 day14:10

14:10

Friday Episode with Alexander Schacht Key Points: Building Influence Negotiation Trust Pillars Collaboration Proactivity Impact Actionable Strategies Building influence as a statistician isn’t just about being heard—it’s about driving better decisions, improving team dynamics, and ultimately making a greater impact on patient outcomes. The strategies I share in this episode will help you strengthen your influence, gain trust, and collaborate more effectively. So don’t just listen—take action! Tune in now, and if you found this valuable, share it with friends and colleagues who can benefit. And if you’re serious about leveling up your leadership skills, check out the Medical Data Leaders Community (MDLC) for expert guidance and a network of like-minded professionals.…

The Effective Statistician - in association with PSI

1
Effective self-management and taking care of your mental health 31:00

منذ 4 أيام31:00

31:00

Interview with Peter M. Wehmeier Key Points: Workload & Mental Well-being Five Dimensions of Self-Management Relationships Priorities Decision-Making Taking Action Stress Management Peter’s Workshops Empowerment Take control of your well-being and success by mastering self-management. In this episode, you’ll learn practical strategies to reduce stress, build resilience, and stay productive. Listen now and start making positive changes today. If you found this discussion helpful, share it with friends and colleagues who need to hear it. Let’s support each other in creating healthier, more effective careers! I’m thrilled to share that my book, “How to Be an Effective Statistician – Volume 1” , is now available! It’s packed with insights to help statisticians, data scientists, and quantitative professionals excel as leaders, collaborators, and change-makers in healthcare and medicine. Check out the testimonials and grab your copy! Boost Your Leadership with MDLC ! The Medical Data Leaders Community (MDLC) gives you the tools and support to grow your leadership skills, expand your influence, and drive meaningful change in healthcare research. Whether you're just starting or already leading a team, this community helps you take your career to the next level Learn more here!…

The Effective Statistician - in association with PSI

1
Taming AI for Biostatistics: Darko Medin on Bio AI Works & Reliable AI Models 28:38

منذ 8 أيام28:38

28:38

Interview with Darko Medin Key Points: AI Challenges: Hallucinations, Accuracy, Reliability AI Solutions: Validation, Cross-checking, Domain-specific rules Use Cases: Oncology, Precision Medicine, Drug Discovery High-dimensional Data: Hidden patterns, Complex datasets AI Agents: Semi-autonomous, Goal-driven, Multi-step processes Interpretability vs. Explainability: Statistical rigor, Scientific validation Future of AI: Scaling, Faster iteration, Reliable outputs Artificial intelligence is rapidly transforming biostatistics, but ensuring its accuracy and reliability remains a critical challenge. In this episode, Darko Medin shares valuable insights into how Bio AI Works is tackling these issues, from reducing hallucinations in large language models to uncovering hidden patterns in complex datasets. If you’re interested in how AI can enhance statistical rigor and drive innovation in fields like oncology and precision medicine, you won’t want to miss this conversation. Tune in now, and if you found this episode insightful, share it with your friends and colleagues who would benefit from learning about AI’s role in biostatistics! I’m thrilled to share that my book, “How to Be an Effective Statistician – Volume 1” , is now available! It’s packed with insights to help statisticians, data scientists, and quantitative professionals excel as leaders, collaborators, and change-makers in healthcare and medicine. Check out the testimonials and grab your copy! Boost Your Leadership with MDLC ! The Medical Data Leaders Community (MDLC) gives you the tools and support to grow your leadership skills, expand your influence, and drive meaningful change in healthcare research. Whether you're just starting or already leading a team, this community helps you take your career to the next level Learn more here!…

The Effective Statistician - in association with PSI

1
Slow Productivity 31:52

منذ 11 يومًا31:52

31:52

A book review with Steve Mallett and Alun Bedding Key Points: Slow Productivity Three Principles Workload Management Meetings Seasonality Overhead Tax Quality vs. Perfectionism Time Management Mindset Shift Slow Productivity offers valuable insights on working smarter, not just harder. By applying its principles, we can reduce stress, improve focus, and create higher-quality work. Tune in to this episode to hear practical tips from Alun, Steve, and me on making these ideas work in real life. If you find this discussion helpful, share it with your friends and colleagues so they can benefit too! I’m thrilled to share that my book, “How to Be an Effective Statistician – Volume 1” , is now available! It’s packed with insights to help statisticians, data scientists, and quantitative professionals excel as leaders, collaborators, and change-makers in healthcare and medicine. Check out the testimonials and grab your copy! Boost Your Leadership with MDLC ! The Medical Data Leaders Community (MDLC) gives you the tools and support to grow your leadership skills, expand your influence, and drive meaningful change in healthcare research. Whether you're just starting or already leading a team, this community helps you take your career to the next level Learn more here!…

The Effective Statistician - in association with PSI

1
Behind the Scenes of Writing a Book About Casual Inference 23:15

منذ 18 يومًا23:15

23:15

Interview with Justin Belair Key points: Causal Inference – Hot topic in statistics Justin Belair – Guest, statistician, book author Book Writing – Motivation, challenges, process Balancing Content – Theory, real-world applications, coding exercises Effective Writing – Strategies, focus, overcoming obstacles Practical Tools – Applying causal inference in work Inspiration – Insights for statisticians and aspiring authors Tune In – Engaging discussion, learning opportunity Writing a book on a complex topic like causal inference takes dedication, clarity, and a deep understanding of both theory and practice. In this episode, Justin Belair shares his journey, insights, and practical strategies for mastering causal inference and making statistical concepts more accessible. Whether you're a statistician, data scientist, or simply curious about this evolving field, you’ll gain valuable takeaways that can enhance your work. Don’t miss out—tune in now to hear our full conversation! And if you found this episode helpful, share it with your friends and colleagues who could benefit from Justin’s insights. I’m thrilled to share that my book, “How to Be an Effective Statistician – Volume 1” , is now available! It’s packed with insights to help statisticians, data scientists, and quantitative professionals excel as leaders, collaborators, and change-makers in healthcare and medicine. Check out the testimonials and grab your copy! Boost Your Leadership with MDLC ! The Medical Data Leaders Community (MDLC) gives you the tools and support to grow your leadership skills, expand your influence, and drive meaningful change in healthcare research. Whether you're just starting or already leading a team, this community helps you take your career to the next level Learn more here! In this episode, Justin Belair shares his journey, insights, and practical strategies for mastering causal inference and making statistical concepts more accessible. Whether you're a statistician, data scientist, or simply curious about this evolving field, you’ll gain valuable takeaways that can enhance your work. Don’t miss out—tune in now to hear our full conversation! And if you found this episode helpful, share it with your friends and colleagues who could benefit from Justin’s insights. Check out his book here: Causal Inference in Statistics with Exercises, Practice Projects, and R Code Notebooks…

The Effective Statistician - in association with PSI

1
What Is The MDLC and How It Will Help You? 13:32

منذ 25 يومًا13:32

13:32

Discussion with Alexander Schacht Key points MDLC Introduction Leadership Growth Career Development Three Tiers Learning Formats Real-World Application Impact on Healthcare Membership Options How to Join The Medical Data Leaders Community (MDLC) offers a unique opportunity to grow your leadership skills, expand your influence, and drive meaningful change in healthcare research. Whether you're just starting or leading a team, this community provides the tools and support you need to advance your career. Don’t miss out—tune in to this episode of The Effective Statistician to learn more about how MDLC can help you. If you find this episode valuable, share it with your colleagues and network so they can benefit too. Let’s build a stronger, more impactful data community together!…

The Effective Statistician - in association with PSI

1
Endless To-Do Lists 16:42

منذ 29 يومًا16:42

16:42

Friday Episode with Alexander Schacht Key points Endless To-Do Lists Causes of Overload Problems Key Strategies: Prioritization Single Bridge System Task Breakdown Say No & Delegate Two-Minute Rule Big-Picture Thinking Leadership Skills Medical Data Leaders Community Call to Action Take back control of your time and break free from endless to-do lists. Listen to this episode of The Effective Statistician to learn practical strategies that help you prioritize, delegate, and make real progress. Don’t keep these insights to yourself—share this episode with friends and colleagues who need a smarter way to manage their workload. Start making a real impact today! I’m thrilled to share that my book, “How to Be an Effective Statistician – Volume 1” , is now available! It’s packed with insights to help statisticians, data scientists, and quantitative professionals excel as leaders, collaborators, and change-makers in healthcare and medicine. Check out the testimonials and grab your copy! Check out the testimonials and grab your copy here!…

The Effective Statistician - in association with PSI

1
Struggling With A Full Calendar? 14:05

منذ 5 weeks14:05

14:05

Discussion with Alexander Schacht Key points: Meeting Overload Root Causes Impact Strategy 1: Priorities Strategy 2: Meeting Practices Strategy 3: Saying No Long-Term Approach Bonus Take back control of your calendar and focus on what truly matters. Set clear priorities, improve meeting practices, and say no to unnecessary commitments. These strategies will help you create more time for deep work, reduce stress, and boost productivity. Listen to this episode of The Effective Statistician now and start making real changes today. If you found it helpful, share it with your friends and colleagues so they can also take charge of their time! Join me for a free webinar , How to Be an Effective Statistician ! Wednesday, February 5th, at 5 PM CET! Learn how to boost your efficiency, manage your workload, and improve your work-life balance with practical tips you can apply immediately. I’ll share proven strategies from the book How to Be an Effective Statistician to help you thrive in your career and make a bigger impact. Don’t miss this opportunity to enhance your skills and grow as a statistician. Register now and invite your colleagues to join! I want to register!…

The Effective Statistician - in association with PSI

1
Breaking Free from the Beliefs Keeping You Stuck in Long Hours 17:57

منذ 5 weeks17:57

17:57

Friday Episode with Alexander Schacht Key points Key Points from the Episode: Long Hours Trap Workload Pressure Belief Shifts Limiting Beliefs: "Hard Work = Value" "Busyness = Productivity" "Perfectionism" "Delegation is Weakness" Productivity Strategies: Prioritization Meetings Communication Automation & Templates Career Impact Health & Relationships Upcoming Webinar If you feel stuck working long hours, it's time to break free from the beliefs holding you back. In this episode, I share practical strategies to help you work smarter, deliver better results, and build a healthier work-life balance. Don’t let overwork stall your career or drain your energy—listen now to The Effective Statistician and start making real changes today. If you find this episode valuable, share it with your friends and colleagues so they can benefit too. Together, we can create a more effective and balanced way to work! Join me for a free webinar , How to Be an Effective Statistician ! Wednesday, February 5th, at 5 PM CET! Learn how to boost your efficiency, manage your workload, and improve your work-life balance with practical tips you can apply immediately. I’ll share proven strategies from the book How to Be an Effective Statistician to help you thrive in your career and make a bigger impact. Don’t miss this opportunity to enhance your skills and grow as a statistician. Register now and invite your colleagues to join! I want to register!…

The Effective Statistician - in association with PSI

1
What Are GAMS and How Can You Leverage Them? 18:39

منذ 6 weeks18:39

18:39

Interview with Steve Dirkse Key Points: GAMS Overview Distinction Applications System Components Examples Mathematical Functions Convexity Getting Started Documentation and Training Final Advice GAMS opens up a world of possibilities for solving complex optimization problems, from logistics and healthcare to business and beyond. Whether you're a statistician, data scientist, or simply someone tackling intricate systems, this episode offers valuable insights and practical advice to get started with this powerful tool. If you found this discussion helpful, take a moment to listen to the full episode and dive deeper into how GAMS can transform your work. Don’t forget to share this episode with your friends and colleagues who could benefit from these insights. Together, let’s spread the knowledge and make optimization more effective for everyone!…

The Effective Statistician - in association with PSI

1
Why Becoming a Long-Haul Leader Matters 20:20

منذ 6 weeks20:20

20:20

Discussion with Alexander Schacht Key points Hustle Culture Mental and Physical Health Long-Haul Leadership Continuous Personal Growth Adaptability and Change Nurturing Relationships Values and Principles Prioritizing Well-Being Building Consensus Leaving a Legacy Adopting the mindset of a long-haul leader isn’t just about improving your work—it’s about transforming your entire approach to life and career. By focusing on sustainability, growth, and well-being, you can build a fulfilling, impactful future without falling into the burnout trap. If you’re ready to make this shift and take control of your career for the long term, this episode is for you. Listen now to discover practical strategies for thriving as a long-haul leader. If you find this episode valuable, don’t keep it to yourself—share it with your friends, colleagues, and anyone who could benefit from these insights. Together, we can create a healthier, more balanced approach to work. Tune in and start your journey today!…

The Effective Statistician - in association with PSI

1
Negotiation for Statisticians: Advocating for Yourself and Your Work 20:08

منذ 7 weeks20:08

20:08

Discussion with Alexander Schacht Key points Negotiation as an Essential Skill Examples of Negotiation Importance of Preparation Effective Strategies Professional Impact Broader Application Practical Insights Negotiation transforms your professional and personal interactions, empowering you to advocate for yourself and achieve better outcomes. In this episode, I share actionable strategies and insights that help you master negotiation and boost your impact as a statistician. Don’t miss these valuable tips—listen now! Share this episode with friends and colleagues who can benefit, and let’s empower more statisticians to succeed together! Join me for a free webinar , How to Be an Effective Statistician ! Thursday, February 5th, at 5 PM CET! Learn how to boost your efficiency, manage your workload, and improve your work-life balance with practical tips you can apply immediately. I’ll share proven strategies from the book How to Be an Effective Statistician to help you thrive in your career and make a bigger impact. Don’t miss this opportunity to enhance your skills and grow as a statistician. Register now and invite your colleagues to join! I want to register!…

The Effective Statistician - in association with PSI

1
Trust 23:29

منذ 7 weeks23:29

23:29

Friday Episode with Alun Bedding Key Points: Trust as Leadership Backbone Leadership is a Choice Leadership vs. Management Authenticity Inspiration vs. Motivation Trust Equation Nine Habits of Trust: Deliver Be open Be honest Be brave Coach Be humble Evangelize Be consistent Be kind Trust is Earned Empathy and Kindness Trust as a Bank Account Trust is the foundation of leadership, inspiration, and meaningful connections, and this episode offers invaluable insights into building it effectively. From understanding the habits of trust to choosing authenticity and kindness, Alun Bedding provides actionable advice that can transform how you lead and influence others. Don’t miss this opportunity to enhance your personal and professional impact—listen to the full episode now! If you find the discussion helpful, share it with your friends and colleagues who can benefit from learning how to cultivate trust in their own lives. Together, let’s spread the power of trust and make a difference! Join me for a free webinar , How to Be an Effective Statistician ! Thursday, February 5th, at 5 PM CET! Learn how to boost your efficiency, manage your workload, and improve your work-life balance with practical tips you can apply immediately. I’ll share proven strategies from the book How to Be an Effective Statistician to help you thrive in your career and make a bigger impact. Don’t miss this opportunity to enhance your skills and grow as a statistician. Register now and invite your colleagues to join! I want to register!…

The Effective Statistician - in association with PSI

1
Behind the Pages: How I Wrote 'How to Be an Effective Statistician' 11:06

منذ 8 weeks11:06

11:06

Discussion with Alexander Schacht Key points New Year Episode Book Announcement Personal Journey Target Audience Content Overview Fictional Narrative Chapter Structure Book Format Launch Party Ordering Info Don’t miss this inspiring episode of The Effective Statistician ! Whether you’re curious about the process of writing a book, looking for actionable career insights, or simply eager to learn more about How to Be an Effective Statistician , this conversation has something for you. Tune in now to hear the full story behind the book, and be sure to share this episode with your friends and colleagues. Let’s work together to empower statisticians and other quantitative professionals to make a greater impact in their fields!…

The Effective Statistician - in association with PSI

1
Imposter Syndrome 16:54

منذ 8 weeks16:54

16:54

Friday Episode with Alun Bedding Key Points: Imposter Syndrome Personal Experience Self-Doubt Chimp Paradox (Dr. Steve Peters) Inner Chimp Confidence Slowing Down Reframing Negative Experiences Learning Opportunities Recognizing Strengths Building Confidence Growth Mindset Success Recognition Feedback as a Gift Managing Self-Doubt Actionable Strategies Empowerment If you’ve ever struggled with imposter syndrome, this episode is a must-listen. Alun’s insights and practical strategies offer a refreshing approach to overcoming self-doubt and building confidence in your career. Take a moment to pause, reflect, and recognize your strengths as you listen to this empowering conversation. Don’t keep this valuable advice to yourself—share the episode with your friends and colleagues so they can benefit from it too. Subscribe to The Effective Statistician podcast for more helpful insights and be sure to spread the word to help others navigate their imposter syndrome with confidence.…

مرحبًا بك في مشغل أف ام!

يقوم برنامج مشغل أف أم بمسح الويب للحصول على بودكاست عالية الجودة لتستمتع بها الآن. إنه أفضل تطبيق بودكاست ويعمل على أجهزة اندرويد والأيفون والويب. قم بالتسجيل لمزامنة الاشتراكات عبر الأجهزة.