DNA methylation & epigenetic reprogramming during development with Dr Maxim Greenberg

The Genomics Lab

Join us today as we speak to Dr Maxim Greenberg, located at the Institut Jacques Monod in the heart of Paris. IJM is one of the premier institutes for fundamental research in the life sciences in France. Maxim's lab aims to better understand the epigenetic consequences of DNA methylation during a specific window of development which occurs in the first week of embryogenesis but ripples throughout life. Another aim of the Greenberg lab is to better understand what DNAme is doing when it is not at promoters? And its corollary: how do promoters stay DNA methylation free?

Today we discuss several of Maxims publications (linked below), the function of DNA methylation and the process of DNA methylation deposition and removal. Maxim also gives us an interesting insight into the details of how his lab aim to better understand epigenetic reprogramming in development.

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Maxims Lab website

Publications discussed in todays episode are linked below:

Greenberg M.V.C. (2021) Get Out and Stay Out: New Insights Into DNA Methylation Reprogramming in Mammals. Frontiers in Cell and Developmental Biology

The diverse roles of DNA methylation in mammalian development and disease.