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How to Control Your Sense of Pain & Pleasure

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Manage episode 299480399 series 2849974
المحتوى المقدم من Scicomm Media. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرةً بواسطة Scicomm Media أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.

This episode I discuss our sense of pain and pleasure: where and how they each arise in our mind and body and various ways to control their intensity. I discuss the science of behavioral tools like acupuncture and hypnosis and directed pressure, including the neural circuits they each activate to modulate our experience of pain or pleasure. I also discuss whole body pain, pain "syndromes" and novel pain relief compounds such as Acetyl-L-Carnitine, SAMe and Agmatine. I discuss neuroplasticity of the pain system and the key role that visual perception plays in pain modulation. Finally, I address the link between dopamine, serotonin, and oxytocin, with arousal, pleasure and pain. As always, both basic science and various protocols are described.

Note: The description of the dorsal root ganglia (DRGs) was intentionally simplified and does not include mention of dorsal horn spinal relay neurons, etc. For an excellent full text review of this anatomy and circuits for touch sensing, please see: https://bit.ly/3jH9CPf

For the full show notes, visit hubermanlab.com.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

LMNT: https://drinklmnt.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

Timestamps

(00:00:00) Skin, Pain, Pleasure

(00:01:50) Protocol 1: Maximizing Motivation (with Dopamine & Pleasure)

(00:07:29) Sponsors: AG1, LMNT

(00:12:04) Pleasure & Pain, & Skin Sensors

(00:18:13) Sensing Touch with Your Brain: Magnification of Feet, Hands, Lips, Face, Genitals

(00:22:16) Two-Point Discrimination, Dermatomes

(00:28:11) Thoughts & Genes That Make Physical Pain Worse

(00:33:45) Expectations, Anxiety, & Pain Threshold

(00:40:27) Protocol 2: Cold Sensing Is Relative; Getting Into Cold Water

(00:45:22) Protocol 3: Heat Is Absolute

(00:48:10) Injury & Pain

(00:52:04) Protocol 4: Plasticity of Pain: Key Role of Vision

(00:58:08) Sensing Disparate Body Parts As Merged

(01:01:00) Pain “Syndromes”, Psychogenic Fever, “Psychosomatics”

(01:04:40) Fibromyalgia, Naltrexone, Protocol 5: Acetyl-L-Carnitine

(01:12:24) Protocol 6: Agmatine, S-adenosyl-L-methionine (SAMe), L-5-Methyltetrahydrofolate*

(01:17:27) Acupuncture: Mechanism, Non-Responders, Itch & Inflammation

(01:28:20) Laser Photobiomodulation, Protocol 7: Hypnosis (reveri.com)

(01:30:00) Protocol 8: Pressure-Based Pain Relief, “Gate Theory of Pain (Relief)”

(01:37:53) Redheads & Pain Thresholds, Endogenous Opioids

(01:44:02) Protocol 8: Love & Pain, Dopamine

(01:49:23) Pleasure & Reproduction, Dopamine & Serotonin, Oxytocin

(01:51:40) Protocol 9: PEA, L-Phenylalanine (Precursor to Tyrosine)

(01:55:40) Contextual Control of Pleasure by Autonomic Arousal, Dopamine Baselines

(01:59:40) Pleasure-Pain Balance

(02:01:24) Protocol 10: Controlling Pleasure, Dopamine & Motivation Over Time

(02:06:40) Protocol 11: Immediate, Non-Goal-Directed Pleasure, PAG

(02:08:40) Direction of Touch: Pleasure Versus Pain, Arousal & Touch “Sensitivity”

(02:13:00) Synthesis & How to Conceptualize Pain and Pleasure, Support

Title Card Photo Credit: Mike Blabac

Disclaimer

  continue reading

205 حلقات

Artwork

How to Control Your Sense of Pain & Pleasure

Huberman Lab

6,436 subscribers

published

iconمشاركة
 
Manage episode 299480399 series 2849974
المحتوى المقدم من Scicomm Media. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرةً بواسطة Scicomm Media أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.

This episode I discuss our sense of pain and pleasure: where and how they each arise in our mind and body and various ways to control their intensity. I discuss the science of behavioral tools like acupuncture and hypnosis and directed pressure, including the neural circuits they each activate to modulate our experience of pain or pleasure. I also discuss whole body pain, pain "syndromes" and novel pain relief compounds such as Acetyl-L-Carnitine, SAMe and Agmatine. I discuss neuroplasticity of the pain system and the key role that visual perception plays in pain modulation. Finally, I address the link between dopamine, serotonin, and oxytocin, with arousal, pleasure and pain. As always, both basic science and various protocols are described.

Note: The description of the dorsal root ganglia (DRGs) was intentionally simplified and does not include mention of dorsal horn spinal relay neurons, etc. For an excellent full text review of this anatomy and circuits for touch sensing, please see: https://bit.ly/3jH9CPf

For the full show notes, visit hubermanlab.com.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

LMNT: https://drinklmnt.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

Timestamps

(00:00:00) Skin, Pain, Pleasure

(00:01:50) Protocol 1: Maximizing Motivation (with Dopamine & Pleasure)

(00:07:29) Sponsors: AG1, LMNT

(00:12:04) Pleasure & Pain, & Skin Sensors

(00:18:13) Sensing Touch with Your Brain: Magnification of Feet, Hands, Lips, Face, Genitals

(00:22:16) Two-Point Discrimination, Dermatomes

(00:28:11) Thoughts & Genes That Make Physical Pain Worse

(00:33:45) Expectations, Anxiety, & Pain Threshold

(00:40:27) Protocol 2: Cold Sensing Is Relative; Getting Into Cold Water

(00:45:22) Protocol 3: Heat Is Absolute

(00:48:10) Injury & Pain

(00:52:04) Protocol 4: Plasticity of Pain: Key Role of Vision

(00:58:08) Sensing Disparate Body Parts As Merged

(01:01:00) Pain “Syndromes”, Psychogenic Fever, “Psychosomatics”

(01:04:40) Fibromyalgia, Naltrexone, Protocol 5: Acetyl-L-Carnitine

(01:12:24) Protocol 6: Agmatine, S-adenosyl-L-methionine (SAMe), L-5-Methyltetrahydrofolate*

(01:17:27) Acupuncture: Mechanism, Non-Responders, Itch & Inflammation

(01:28:20) Laser Photobiomodulation, Protocol 7: Hypnosis (reveri.com)

(01:30:00) Protocol 8: Pressure-Based Pain Relief, “Gate Theory of Pain (Relief)”

(01:37:53) Redheads & Pain Thresholds, Endogenous Opioids

(01:44:02) Protocol 8: Love & Pain, Dopamine

(01:49:23) Pleasure & Reproduction, Dopamine & Serotonin, Oxytocin

(01:51:40) Protocol 9: PEA, L-Phenylalanine (Precursor to Tyrosine)

(01:55:40) Contextual Control of Pleasure by Autonomic Arousal, Dopamine Baselines

(01:59:40) Pleasure-Pain Balance

(02:01:24) Protocol 10: Controlling Pleasure, Dopamine & Motivation Over Time

(02:06:40) Protocol 11: Immediate, Non-Goal-Directed Pleasure, PAG

(02:08:40) Direction of Touch: Pleasure Versus Pain, Arousal & Touch “Sensitivity”

(02:13:00) Synthesis & How to Conceptualize Pain and Pleasure, Support

Title Card Photo Credit: Mike Blabac

Disclaimer

  continue reading

205 حلقات

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