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The Wednesday Season 2 Official Woecast


1 Here We Woe Again: Jenna Ortega, Creators Al Gough & Miles Millar 31:46
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BE WARNED! This podcast will contain spoilers for Wednesday Season 2, episodes 1-4. Join host Caitlin Reilly each week as she takes you deep into the twisted world of Wednesday with an amazing group of guests! And producer Thing will be helping out to make sure everything goes to plan - well, mostly, anyway... In this episode: Jenna Ortega peels back the layers on the new tension between Wednesday and Enid. And that terrifying vision! Plus… Series showrunners Al Gough and Miles Millar reveal why they made Morticia Addams such a central character in this season, and what it means for Wednesday. Whether you’re a normie or an outcast, the Wednesday Season 2 Official Woecast will be the place for all things Nevermore! For more juicy details about Wednesday Season 2, head over to Tudum.com to get all of the latest updates. 1:15 Preparing for Season 2 3:25 Evolving Wednesday’s look for Season 2 4:12 Addams clan expands for Season 2 6:12 Joanna Lumley joining the cast 7:38 Wednesday and Enid's Friendship 9:00 Wednesday’s Vision 10:50 Jenna is a Producer 13:45 Al and Miles introduction 14:03 Wednesday takes down a Serial Killer 15:05 Intergenerational Relationships & the Addams Women 17:48 Catherine Zeta-Jones as Morticia in Season 2 20:48 Wednesday and Enid’s relationship 24:04 Steve Buscemi joining the cast 26:19 Wednesday’s popular! 27:45 Boy with the Clockwork Heart stop motion sequence…
Yale Journal of Biology and Medicine
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المحتوى المقدم من YaleUniversity. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرة بواسطة YaleUniversity أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.
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111 حلقات
وسم كل الحلقات كغير/(كـ)مشغلة
Manage series 2441900
المحتوى المقدم من YaleUniversity. يتم تحميل جميع محتويات البودكاست بما في ذلك الحلقات والرسومات وأوصاف البودكاست وتقديمها مباشرة بواسطة YaleUniversity أو شريك منصة البودكاست الخاص بهم. إذا كنت تعتقد أن شخصًا ما يستخدم عملك المحمي بحقوق الطبع والنشر دون إذنك، فيمكنك اتباع العملية الموضحة هنا https://ar.player.fm/legal.
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1 YJBM Epigenetics: Interview with Deputy Editors 32:00
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In this episode, we go behind the scenes with Reem and Adriana, the deputy editors who led the Yale Journal of Biology and Medicine's special issue on Epigenetics. Our hosts Isha and Delyar discuss the editors’ experience in facing new frontiers in scientific publishing, including developing protocols to detect AI-generated content and ensuring manuscripts contribute meaningfully to the scientific consensus. Read the “Epigenetics” issue: https://medicine.yale.edu/news-article/explore-yjbms-june-2025-issue-on-epigenetics/ Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 Kinase Pathways Driving the Future of Tick Control: Interview with Emily Johnson 46:15
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Could hacking a tick’s biology help prevent the next outbreak? In this episode of the YJBM, we sit down with Emily Johnson to travel across the scale of life, all the way from the environment that surrounds us to a molecular pathway called kinase signaling. We dive into the fundamentals of vector biology and the transmission of diseases like Lyme. We also discuss the tools and technologies driving the field forward, from mRNA vaccines to the potential of AI, and what the future holds for understanding disease and transmission through the lens of signaling pathways. Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 YJBM Science News 34: All About Organs 35:05
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In this week’s episode of the YJBM Science News podcast, co-hosts Hanna and Roxanna explore papers that take us all around different organs in the body! Can we 3D print functional blood vessels? How does the brain spy on our organs? Find out the answers to these questions and more as we discuss recent Yale-affiliated research in biology and medicine. Papers featured in this episode: "Development and deployment of a functional 3D-bioprinted blood vessel”: https://doi.org/10.1038/s41598-025-93276-y https://medicine.yale.edu/news-article/scientists-successfully-implant-bioprinted-aorta-in-rats/ "Typhoid toxin causes neuropathology by disrupting the blood–brain barrier”: https://doi.org/10.1038/s41564-025-02000-z https://news.yale.edu/2025/05/09/how-typhoid-fever-triggers-severe-neurological-symptoms “Adaptation to Volumetric Compression Drives an Apoptosis-Resistant and Invasive Phenotype in Liver Cancer”: https://doi.org/10.1158/0008-5472.CAN-24-0859 https://medicine.yale.edu/news-article/new-study-finds-that-physical-pressure-escalates-liver-cancer-aggression/ “The subfornical organ is a nucleus for gut-derived T cells that regulate behaviour”: https://doi.org/10.1038/s41586-025-09050-7 https://doi.org/10.1038/d41586-025-01655-2 https://medicine.yale.edu/news-article/t-cells-take-up-residence-in-the-healthy-brain-via-a-gut-fat-brain-axis/ Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 YJBM Kinase Signaling: Interview with Deputy Editors 26:43
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Get insight into the work that went into the most recent YJBM issue, ‘Kinase Signaling’! In this episode, our hosts Shivesh Shourya and Shivani Dayal speak to this issue’s deputy editors Ingrid Heumann and Rahul Gupta to discuss early challenges in the process of creating this issue, publishing new work in the basic sciences, and future directions in the field of kinase signaling, and what they hope readers take away from this issue. Read the “Kinase Signalling” issue: https://medicine.yale.edu/news-article/kinase-signaling-is-focus-of-the-march-2025-yjbm-issue/ Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 YJBM Science News 33: Surroundings, Access, and Health 34:00
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This week’s episode of YBJM Science News discusses how our surroundings impact a variety of health outcomes. From air pollutants to sleep quality to pharmacy access and more, join Roxanna and Hanna as they discuss recent Yale-affiliated research in biology and medicine. Papers featured in this episode and associated links: “Early-Life Exposure to Air and Light Pollution Linked to Increased Risk of Pediatric Thyroid Cancer” - https://ysph.yale.edu/news-article/early-life-exposure-to-air-and-light-pollution-linked-to-increased-risk-of-pediatric-thyroid-cancer “Perinatal Exposures to Ambient Fine Particulate Matter and Outdoor Artificial Light at Night and Risk of Pediatric Papillary Thyroid Cancer” - https://doi.org/10.1289/EHP14849 New York Times article on Environmental Health Perspectives journal - https://www.nytimes.com/2025/04/29/science/science-journal-environment-trump.html “Reduced Deep and REM Sleep Could be Early Markers of Alzheimer’s” - https://medicine.yale.edu/news-article/reduced-deep-and-rem-sleep-could-be-early-markers-of-alzheimers/ “Lower slow wave sleep and rapid eye movement sleep are associated with brain atrophy of AD-vulnerable regions” - https://doi.org/10.5664/jcsm.11630 The Atherosclerosis In the Community Study - https://www5.cscc.unc.edu/aric9/ “Groundbreaking Study Highlights Critical Gap in Global Mental Health Research” - https://medicine.yale.edu/psychiatry/news-article/groundbreaking-study-highlights-critical-gap-in-global-mental-health-research/ “Psychiatric genetics in the diverse landscape of Latin American populations” - https://doi.org/10.1038/s41588-025-02127-z Latin American Genomics Consortium - https://www.latinamericangenomicsconsortium.org/ “A New Metric to Identify – and Prevent – Pharmacy Deserts” - https://medicine.yale.edu/news-article/a-new-metric-to-identify-prevent-pharmacy-deserts/ “Vulnerability Index Approach to Identify Pharmacy Deserts and Keystone Pharmacies” - https://doi.org/10.1001/jamanetworkopen.2025.0715 “Timing of RSV Immunization Matters for Infant Protection” - https://medicine.yale.edu/news-article/timing-of-rsv-immunization-matters-for-infant-protection/ “Estimated Effectiveness of Nirsevimab Against Respiratory Syncytial Virus” - https://doi.org/10.1001/jamanetworkopen.2025.0380 Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 Host-Virus Interactions in the Human Airway: Interview with Tim Watkins 28:18
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Why is a lower impact of COVID-19 seen in children compared to adults? In this episode of the YJBM podcast, co-hosts Delyar Khosroabadi and Amy Guan speak with Timothy Watkins, a graduate student in the laboratory of Dr. Ellen F. Foxman at the Yale School of Medicine. He shares what initially drew him to research and how his journey has evolved across disciplines. Tim also discusses the importance of understanding host-virus interactions, mechanisms underlying heightened nasal innate immunity in children, and some of the challenges he encounters in his work.…

1 Secret Signals: How the Body Repairs, Reacts, and Reflects 28:24
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This week’s episode of YBJM Science News tackles two important parts of our bodies: skin and brain. From immune cells to lysosomes to brain networks and more, join co-hosts Majo and Hanna as they break down recent Yale-affiliated biological and biomedical research. Papers featured in this episode: Skin Injury May Bring on Food Allergies https://medicine.yale.edu/news-article/skin-injury-may-bring-on-food-allergies/ Skin damage signals mediate allergic sensitization to spatially unlinked antigen https://www.science.org/doi/10.1126/sciimmunol.adn0688 Neutrophils in the Immune System Help Build Healthy Skin https://medicine.yale.edu/news-article/neutrophils-in-the-immune-system-help-build-healthy-skin/?utm_source=YaleToday&utm_medium=email&utm_campaign=YT_YaleToday-Students_4-7-2025 Matrix-producing neutrophils populate and shield the skin https://www.nature.com/articles/s41586-025-08741-5 Damaged Cell ‘Trash Cans’ May Contribute to Parkinson’s Disease https://medicine.yale.edu/news-article/damaged-cell-trash-cans-may-contribute-to-parkinsons-disease/ The bridge-like lipid transport protein VPS13C/PARK23 mediates ER-lysosome contacts following lysosome damage https://www.nature.com/articles/s41556-025-01653-6 Understanding the Transition from Early to Chronic Psychosis https://medicine.yale.edu/news-article/understanding-the-transition-from-early-to-chronic-psychosis/ Connectome-based predictive modeling of early and chronic psychosis symptoms https://www.nature.com/articles/s41386-025-02064-9…

1 YJBM Science News 31: Clues to Cancer Care 24:41
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This week’s episode of the YJBM Science News podcast is all about papers that identify or help narrow down potential new targets and tools for cancer therapeutics. From protein modifications to autoantibodies to epigenetic markers and more, join co-hosts Majo and Roxanna as they break down recent Yale-affiliated biological and biomedical research. Papers featured in this episode: “Turnover atlas of proteome and phosphoproteome across mouse tissues and brain regions” - https://doi.org/10.1016/j.cell.2025.02.021 https://medicine.yale.edu/news-article/protein-turnover-mapping-may-offer-clues-for-alzheimers-cancer-treatment/ “A lupus-derived autoantibody that binds to intracellular RNA activates cGAS-mediated tumor immunity and can deliver RNA into cells” - https://doi.org/10.1126/scisignal.adk3320 https://medicine.yale.edu/news-article/lupus-related-antibody-shows-promise-in-enhancing-cancer-treatment-efficacy/ “BRCA2 prevents PARPi-mediated PARP1 retention to protect RAD51 filaments” - https://doi.org/10.1038/s41586-025-08749-x https://news.yale.edu/2025/03/26/how-inherited-cancer-risks-can-be-used-effective-personalized-therapy “An in vivo screen identifies NAT10 as a master regulator of brain metastasis” - https://doi.org/10.1126/sciadv.ads6021 https://medicine.yale.edu/news-article/a-genetic-screen-identifies-a-new-master-regulator-of-brain-metastasis/ Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 The Immunology of Long COVID: An Interview with Dr. Lindsay McAlpine and Dr. Keyla Sá 1:01:10
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Why do some individuals continue to experience debilitating neurologic symptoms long after their initial COVID-19 infections? How might our own immune systems be the culprit? In this episode of the YJBM podcast, we learn more about the post-acute infection syndrome known as “long COVID” and the challenges associated with trying to understand its underlying mechanisms. Join co-hosts Shivani and Roxanna as they interview Dr. Lindsay McAlpine and Dr. Keyla Sá, researchers at the Yale University School of Medicine, about their work investigating the pathophysiology of long COVID-associated neurologic symptoms. Papers/preprints mentioned in this interview: “Case-Control Study of Individuals With Small Fiber Neuropathy After COVID-19” - https://doi.org/10.1212/NXI.0000000000200244 “A causal link between autoantibodies and neurological symptoms in long COVID” - https://doi.org/10.1101/2024.06.18.24309100 Keep up with Dr. McAlpine’s work: https://medicine.yale.edu/lab/mcalpine/ https://medicine.yale.edu/neurology/research/covid-mind-study/ https://x.com/mcalpinelabyale https://bsky.app/profile/drlynseymcalpine.bsky.social Keep up with Dr. Sá’s work: https://medicine.yale.edu/lab/iwasaki/ https://x.com/keylas3 https://x.com/VirusesImmunity https://bsky.app/profile/virusesimmunity.bsky.social Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 YJBM Science News 30: Reproductive Health and Immunology 22:27
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In this week’s installment of YJBM Science News, Majo and Roxanna discuss recent Yale-affiliated research about contraceptives, fertility, and immunology! Can our genetic variants help us predict which birth control method would be the most effective? What can the gut microbiome tell us about the immune systems of multiple sclerosis patients before and after undergoing immunotherapy treatment? Join us as we explore not only the answers to these questions, but also as we learn more about the trials and tribulations of data generation! Papers featured in this episode: “Pharmacogenomics of the Etonogestrel Contraceptive Implant: A Genome-Wide Association Study of Steady-State Etonogestrel Concentrations” - https://doi.org/10.1097/og9.0000000000000066 https://medicine.yale.edu/news-article/analyzing-genetics-may-lead-to-better-contraceptive-experiences-for-women/ "Allosteric inhibition of the IZUMO1–JUNO fertilization complex by the naturally occurring antisperm antibody OBF13" - https://doi.org/10.1073/pnas.2425952122 https://news.yale.edu/2025/03/03/scientists-discover-how-naturally-occurring-mechanism-hampers-fertility “A single-cell atlas of circulating immune cells over the first 2 months of age in extremely premature infants” - https://doi.org/10.1126/scitranslmed.adr0942 https://medicine.yale.edu/news-article/new-insights-into-preterm-infant-immunity-could-inform-care/ “Alterations in Gut Microbiome-Host Relationships After Immune Perturbation in Patients With Multiple Sclerosis” - https://doi.org/10.1212/NXI.0000000000200355 https://medicine.yale.edu/news-article/gut-microbiome-changes-linked-to-multiple-sclerosis-ms-new-study-finds/ Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 A Tale of Two Viruses: Interview with Sasha Tabachnikova 44:33
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What do COVID and mono have in common? How can infectious diseases impact our health for life? How does a dancer end up doing basic science research? Join our hosts Isha Yardi and Elaine Yang in conversation with Sasha Tabachnikova about her work as a PhD student in the Iwasaki Lab. Today, she is our guide through the evolving landscape of research on post-acute infection syndromes. Learn about YJBM here: https://medicine.yale.edu/yjbm/ Viruses and Autoimmunity issue: https://medicine.yale.edu/news-article/yjbms-december-2024-issue-focuses-on-viruses-and-autoimmunity/ Our Instagram: https://www.instagram.com/theyjbm/…
Does mRNA play a role in cell migration? Can we use therapeutic vaccines to treat cancers like kidney cancer? Join co-hosts Majo and Roxanna in this week’s installment of YJBM Science News as they discuss the most recent Yale-affiliated biomedical and biological research that answers these questions and more! Papers featured in this episode: “Resolving the three-dimensional interactome of human accelerated regions during human and chimpanzee neurodevelopment” - http://dx.doi.org/10.1016/j.cell.2025.01.007 https://news.yale.edu/2025/02/06/study-sheds-light-genetic-changes-shaped-human-brain-evolution “A neoantigen vaccine generates antitumour immunity in renal cell carcinoma” - https://doi.org/10.1038/s41586-024-08507-5 https://medicine.yale.edu/news-article/personalized-therapeutic-vaccine-steers-the-immune-system-to-fight-kidney-cancer/ “G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration” - https://doi.org/10.1016/j.celrep.2025.115237 https://news.yale.edu/2025/02/13/feet-first-understanding-how-mrna-helps-cells-walk “A human gut bacterium antagonizes neighboring bacteria by altering their protein-folding ability” - https://doi.org/10.1016/j.chom.2025.01.008 https://westcampus.yale.edu/news/2025-02-04-the-hidden-battle-in-your-gut-how-one-bacterium-outsmarts-its-rivals Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…
Welcome back to YJBM Science News! Join us as we discuss the recent news in healthcare and science across the Yale community. Today, Roxanna and our new host Majo will share some of the most intriguing topics of the past few weeks, including the use of AI in diagnostics, cannabinoids as pain therapy, and more! Papers featured in this episode: “Heart failure risk stratification using artificial intelligence applied to electrocardiogram images: a multinational study” - https://doi.org/10.1093/eurheartj/ehae914 https://medicine.yale.edu/news-article/new-ai-tool-identifies-risk-of-future-heart-failure/ “Nav1.8, an analgesic target for nonpsychotomimetic phytocannabinoids” - https://doi.org/10.1073/pnas.2416886122 https://news.yale.edu/2025/01/21/cannabinoids-offer-new-hope-safe-and-effective-pain-relief “Neural Variability and Cognitive Control in Individuals With Opioid Use Disorder” - http://doi.org/10.1001/jamanetworkopen.2024.55165 https://news.yale.edu/2025/01/17/opioid-use-disorder-might-lead-sticky-brains “Atgl-dependent adipocyte lipolysis promotes lipodystrophy and restrains fibrogenic responses during skin fibrosis” - https://doi.org/10.1016/j.jid.2024.12.022 https://news.yale.edu/2025/01/29/fat-cells-play-protective-role-fibrosis-development Read more about YJBM at: https://medicine.yale.edu/yjbm/ Follow us on instagram! https://www.instagram.com/theyjbm/…

1 YJBM Viruses and Autoimmunity: Interview with Deputy Editors 37:53
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Get an exclusive, behind-the-scenes look at the newest YJBM issue! In this episode, our host Shivesh Shourya sits down with deputy editors RuthMabel Boytz and Evan Navori to discuss December’s “Viruses and Autoimmunity.” From the earliest planning stages to navigating unexpected challenges, discover how this issue came to life—and gain fresh insights into the fascinating intersection of viruses and autoimmune disease. Read the “Viruses and Autoimmunity” issue: https://medicine.yale.edu/news-article/yjbms-december-2024-issue-focuses-on-viruses-and-autoimmunity/ More about YJBM at: https://medicine.yale.edu/yjbm/ Our Instagram: https://www.instagram.com/theyjbm/…
Welcome to the first YJBM Science News of the 2025, and welcome our new host, Roxanna Altus! Join us as we discuss the recent news in healthcare and science across the Yale community. Today, our hosts Mara and Roxanna will share some of the most intriguing topics of the past few weeks. Papers featured in the episode: https://www.nature.com/articles/s41556-024-01574-w https://doi.org/10.1016/j.cell.2024.11.037 https://www.nature.com/articles/s41467-025-55902-1 https://www.nature.com/articles/s41586-024-08341-9 More about YJBM at: https://medicine.yale.edu/yjbm/ Our Instagram: https://www.instagram.com/theyjbm/…
مرحبًا بك في مشغل أف ام!
يقوم برنامج مشغل أف أم بمسح الويب للحصول على بودكاست عالية الجودة لتستمتع بها الآن. إنه أفضل تطبيق بودكاست ويعمل على أجهزة اندرويد والأيفون والويب. قم بالتسجيل لمزامنة الاشتراكات عبر الأجهزة.