Chadi welcomes Dr. Andrea Apolo, an internationally recognized leader in bladder cancer research from the National Cancer Institute. Dr. Apolo shares her expertise on recent advancements in urothelial cancer therapy, including key breakthroughs in checkpoint inhibition that have marked a significant turning point in treatment. The conversation delv…

Dr. Joe Mikhael, Chief Medical Officer of the International Myeloma Foundation (IMF) and Professor at TGen, takes us beyond his medical career to explore the personal experiences that have shaped his journey in oncology. Dr. Mikhael discusses the IMF’s targeted strategies for reducing health disparities among diverse ethnic and racial groups affect…

Tom Beer, Chief Medical Officer of the Multi-Cancer Early Detection (MCED) program at Exact Sciences, delves into the groundbreaking science behind MCED tests, which use advanced biomarkers for early detection of multiple cancer types. He explains who may be eligible for these tests, how to interpret results to avoid unnecessary intervention from o…

In this special episode, Chadi gives up the microphone to guest host Kelly Ryerson, who takes over the show asking questions about Chadi's new book "The Cancer Journey."What inspired the book writing? What methods are used? Who is the target audience? What did the author learn? And what did he aim to achieve?Written for everyone who wants to learn …

Jon Chait never thought he would get cancer, but one day he found he had it. As he navigates his journey alongside his caregiver and wife Heather, he shares with Chadi the good and the bad, the ups and downs, and what he encounters in a broken, complex healthcare system.A fitting episode as Chadi launches his book "The Cancer Journey." It is a must…

Kathy Giusti, founder of the Multiple Myeloma Research Foundation (MMRF) and a two-time cancer survivor, opens up about her first diagnosis and the life-changing conversation with her primary care doctor. She reflects on the overwhelming "age of information," which often leads patients to more questions than answers, and shares her strategies for d…

Dr. Joe Lennerz, Chief Scientific Officer of BostonGene and a pathologist by training, joins Chadi to break down next-generation sequencing (NGS) in simple terms, discussing why some patients undergo NGS while others do not, along with its advantages and limitations. He also explores the impact of NGS on treatment pathways, the practicality of mini…

Dr. Sanjay Patel of Weill Cornell and Dr. Greg Goldgof of Memorial Sloan Kettering dive into the transformative role of AI in modern pathology. They discuss how large language models are enhancing diagnostic workflows, expediting report synthesis, and shaping the future of patient care. The conversation also touches on the complex training required…

David Canes, CEO of WellPrept and a Boston-based urologist, joins the show to share the story behind his innovative platform designed to reduce physician burnout. He explains how WellPrept empowers doctors to streamline patient education by organizing and delivering tailored materials before the first visit, allowing for more personalized and effic…

Graduating fellows Jennifer Marks and Megan Melody join the show to discuss the challenges of navigating the job search during fellowship. They share insights on when to start looking for positions, the importance of networking through mentors and conferences, and how to handle geographic limitations in the job market. The conversation also covers …

Yelak Biru, President and CEO of the International Myeloma Foundation (IMF), joins the show to share his remarkable personal and professional journey. After immigrating to the US from Ethiopia, Yelak was diagnosed with multiple myeloma at the age of 26, setting him on an extraordinary path as both a survivor and a passionate advocate for myeloma pa…

Dr. Anish Koka, a cardiologist at Jefferson Health, returns to the show for the first time since the inaugural episode in October 2020. With a sharp focus on healthcare policy, he delves into the impact of the Affordable Care Act on his practice, critiques the influence of political biases in academia, and shares his bold ideas for making healthcar…

Ziad Bakouny, MD, MSc, and Nazli Dizman, MD, return to the show to discuss the progress made for International Medical Graduates (IMGs) within the American Society of Clinical Oncology (ASCO). Building on their previous conversation, they explore the origins of their initiatives at ASCO 2022, the goals for integrating IMGs into successful medical c…

Chadi sits down with Russell Gong, President and CEO of Cabinet Health, and Eric Lessard, Vice President of Pharmacy, to explore their mission to revolutionize the healthcare industry with sustainable practices. They discuss the inspiration behind Cabinet Health, the significance of reducing plastic waste with their eco-friendly refillable medicine…

Dr. Ishwaria Subbiah, Executive Director for Cancer Care Equity and Professional Wellness at the Sarah Cannon Research Institute, joins Chadi to delve into the complexities of professional wellbeing and burnout in the healthcare field. She explores the prevalence of burnout, the concept of "learned helplessness," and effective strategies for improv…

Christian Rolfo, MD, PhD, of Mount Sinai Medical Center, explores the science and clinical applications of liquid biopsies, including circulating tumor DNA. With Chadi, he explains how this cutting-edge approach compares to traditional tissue samples in terms of concordance, sensitivity, and specificity, and expands on the methods used to distingui…

It's July/August and this is the time when residents and fellows start their new chapter of their lives.In this special episode, Chadi tackles the fellowship application process using the "hematology/oncology" fellowship as an example, while keeping the conversation broad to most other fellowships in other disciplines. To better understand the proc…

Chadi is joined by Drs. Rana McKay and Petros Grivas to discuss the latest genitourinary oncology research updates from the 2024 ASCO Annual Meeting, covering topics such as the prognostic ability of KIM-1 in kidney cancer, patient-reported outcomes from enfortumab vedotin/pembrolizumab treatment, and the final overall survival update from the JAVE…

In this exclusive interview, Chadi welcomes Dr. Patrick Soon-Shiong, a Chinese immigrant who grew up under apartheid in South Africa and rose to become one of the world's most successful physician executives. Now the CEO of ImmunityBio, Dr. Soon-Shiong opens up about his remarkable journey. He shares what inspired him to pursue medicine, his entrep…

Drs. Balazs Halmos and Lecia Sequist delve into the groundbreaking updates from the 2024 ASCO Annual Meeting. With Chadi, they reveal game-changing insights on EGFR-mutated lung cancer from the LAURA trial, small-cell lung cancer upgrades from the ADRIATIC trial, important revelations in ALK mutation research, innovative combination therapies, ctDN…

Vivek Subbiah, MD, Chief of Early-Phase Drug Development at Sarah Cannon Research Institute, kicks off his new series on Healthcare Unfiltered, “VIVEK’S TAKES,” in which he will provide his expert feedback on the importance and lasting effects of research presented at the top medical conferences in the world.In response to the 2024 ASCO Annual Meet…

Chadi is joined by Kate Dilligan, Founder and CEO of Cooler Heads Care, the manufacturer of a portable scalp cooling system authorized for adults 21 and older undergoing chemotherapy for a solid tumor. Kate shares her personal journey from being diagnosed with breast cancer to becoming an entrepreneur driven by a mission to help women undergoing ch…

Chadi sits down with David Krissman, a journalist and filmmaker whose passionate advocacy for kidney transplant and dialysis patients led him to create the groundbreaking podcast documentary series, "The Great Social Experiment." Krissman shares the harrowing personal story that inspired his film script, website, and podcast, exposing the stark fin…

Ronald Chapman, LLM, Shareholder and Chairperson of White Collar Defense & Government Investigations at Chapman Law Group, delves into the intricate intersections of law and daily life, highlighting the subspecialized nature of healthcare law and his primary areas of focus within this field. He offers insights into his strategic choices between jud…

Shaalan Beg, MD, MBA, FASCO, and Noelle K. LoConte, MD, FASCO, join Chadi to delve into the contentious relationship between alcohol consumption and cancer. Drawing from their expertise and insights, they navigate through the complexities of discerning causation from association in this context, shedding light on why a randomized controlled trial m…

Chadi is rejoined by special guest Dr. Pamela Kunz, Editor in Chief of the groundbreaking new publication, JCO Oncology Advances. Dr. Kunz, known for her expertise in gastrointestinal cancers, shares the story of how she landed the prestigious role, offering insights into the rigorous interview process. She discusses her innovative approach to gene…

Chadi sits down with Dr. Chandana Banerjee, a trailblazer in palliative and hospice care, serving as the Dean, Director, and Designated Institutional Official of Graduate Medical Education at the City of Hope Comprehensive Cancer Center. With a remarkable career dedicated to improving end-of-life care, Dr. Banerjee shares insights on how to infuse …

Chadi is joined by Stephanie Chuang, a remarkable patient advocate, survivor of non-Hodgkin lymphoma, and the visionary behind The Patient Story, a curator of patients stories and resources for people diagnosed with cancer. Stephanie shares her journey from a surprise diagnosis to the genesis and execution of The Patient Story during her chemothera…

Chadi and guest Dr. Manmeet Ahluwalia, Deputy Director, Chief Scientific Officer, and Chief of Solid Tumor Medical Oncology at Miami Cancer Institute, delve into the latest breakthroughs in primary brain cancers. As a distinguished expert in brain metastases and primary brain tumors, Dr. Ahluwalia provides invaluable insights into clinical trial de…

Chadi delves into the realm of AI and its transformative impact on drug development with Adam Petrich, MD, Chief Medical Officer of QuantHealth, who unveils the AI solutions crafted by QuantHealth, aimed at simulating and predicting clinical trial outcomes to enhance the success rates of trials. Drawing from his expertise, Dr. Petrich sheds light o…

Dr. Aaron Goodman, who started a petition that gathered over 20,000 signatures to end the MOC back in July 2023, found himself suddenly reported as NOT CERTIFIED by the ABIM in the specialty he practices and teaches (hematology). When he called the ABIM, he was told he needed to pay thousands of dollars in back fees for the Internal Medicine Board …

Dr. Grace Cordovano, a distinguished Board Certified Patient Advocate and the visionary founder of Enlightening Results, as well as the co-Founder of Unblock Health, delves into her personal journey, recounting her own wrongful diagnosis of advanced lymphoma and how it propelled her into patient advocacy. Drawing from her extensive experience, she …

Chadi is joined by Simon Arkell, Co-Founder and CEO of Ryght, a pioneering company in the healthcare ecosystem that specializes in producing generative AI solutions that cater specifically to the needs of drug companies. Simon sheds light on the nuances between AI and traditional machine learning models, highlighting Ryght's innovative approach to …

Dr. Paul Teirstein, President of NBPAS.org, joins Chadi to highlight and reveal how the National Board of Physicians and Surgeons (NBPAS) is challenging the status quo of board certification for all medical practitioners. With a mission to advocate for physicians and combat the monopoly of Maintenance of Certification, Dr. Teirstein explains how NB…

In this ASCO-GI research special, Dr. Bekaii-Saab of Mayo Clinic provides an insightful and comprehensive roundup of the most groundbreaking studies unveiled at the ASCO GI 2024 meeting. Delving into the realm of hepatocellular carcinoma, he dissects the pivotal previously-reported data from IMbrave050 and ASCO GI findings from EMERALD-1. Then, he …

Dr. Pedro Barata, Director of the Clinical Genitourinary Medical Oncology Research Program at UH Seidman Cancer Center, provides an exclusive round-up of the most groundbreaking and practice-changing research unveiled at the ASCO GU 2024 meeting. With expertise and insight, he delves into pivotal studies such as CheckMate 914 Part B and KEYNOTE-564…

Joining host Chadi is the esteemed James LaBelle, MD, PhD, Associate Director of Pediatrics and Director of the Stem Cell and Cellular Therapy Program at the University of Chicago. Dr. LaBelle elucidates the complexities of sickle cell disease, unraveling the devastating impact it has on individuals. The episode delves into various treatments and a…

In a poignant episode, USA Today investigative journalist Emily Le Coz unravels the heart-wrenching narrative of Ashleigh Anderson, a CVS pharmacist whose tragic demise serves as a cautionary tale of overwhelming stress in the workplace. Emily shares her motivations behind delving into the pervasive issue of burnout in retail pharmacy and sheds lig…

Joining host Chadi is a trio of esteemed guests – Drs. Andy Evans, Matt Maurer, and Susan Parsons – of the HoLISTIC (Hodgkin Lymphoma International Study for Individual Care) Consortium. In this riveting conversation, they delve into the consortium's pioneering efforts, bringing together an international team of experts to scrutinize the multifacet…

In the latest installment of the ABIM Maintenance of Certification (MOC) saga on Healthcare Unfiltered, the fiery aftermath of Aaron Goodman's groundbreaking petition to dismantle the ABIM MOC takes center stage. Joined by recurring guests, the outspoken Drs. Wes Fisher, Vincent Rajkumar, and Aaron Goodman himself, Chadi dives deep into the shifts …

In a highly-anticipated comeback, Dave Feldman, the seasoned senior software engineer and entrepreneurial mind, delves into uncharted territories of the keto diet, cholesterol dynamics, and lipids, unveiling a riveting discourse intricately intertwined with a novel cardiac study. Feldman unfolds the layers of his personal journey with the keto diet…

Salma Jabbour, MD, Professor and Vice Chair of Radiation Oncology at Rutgers Cancer Institute, provides an invaluable perspective rooted in her extensive experience and passion for radiation oncology. Dr. Jabbour delves into the transformative changes witnessed in radiation oncology over the past two decades, contrasting its trajectory with precisi…

Highlighting the complex and contentious world of non-compete clauses within the medical field, Dr. David Lankford, a pediatric intensivist, made headlines after challenging a non-compete clause in his contract with Lutheran Medical Group in Indiana. His lawsuit not only raises questions about the legality and ethical implications of such clauses, …

Making his return to the show is Dr. Robert Califf, the current FDA Commissioner, this time to break down and offer insights into the Administration’s contentious accelerated approval pathway. Dr. Califf expands on the criticisms and concerns surrounding surrogate endpoints and confirmatory trials within the accelerated approval process, shedding l…

Drs. Hossein Borghaei and Tony Calles dissect the pivotal abstracts and cutting-edge data unveiled at ESMO 2023, spotlighting the transformative landscape of lung cancer treatment. From exploring innovative immunotherapy combinations to the promising prospects of antibody-drug conjugates, they navigate through the complexities of neoadjuvant and ad…

Steve Stavs, a “pro biohacker” and “health futurist,” unveils his model to combat chronic diseases by addressing root causes, while exploring Eastern medicine's approach to preventive care and its current standing in research and empirical evidence for complementary interventions. As a pro biohacker, Stavs shares insights on optimizing whole-body p…

Ameish Govindarajan, MD, a Hospice and Palliative Medicine fellow at Memorial Sloan Kettering Cancer Center, shares his journey outlined in the Journal of Clinical Oncology's Art of Oncology piece, "Chasing Milestones," which sheds light on his personal experience as a patient diagnosed with stage 4 NSCLC. Dr. Govindarajan shares how this diagnosis…

Chadi is joined by experts Jennifer Wargo, MD, Nazli Dizman, MD, and Sumanta (Monty) Pal, MD, from The University of Texas MD Anderson Cancer Center and City of Hope, to unravel the intricate relationship between the microbiome and cancer. Delving into the historical context and evolution of this connection in oncology, they share insights on manip…

Dr. Allison Rosenthal, Assistant Professor of Medicine and a driving force behind Mayo Clinic's Adolescent and Young Adult Cancer Program, candidly shares her personal odyssey as a leukemia survivor during her young adulthood and how this transformative experience steered her career toward advocating for AYA cancer patients. She navigates through c…

Dr. Clifford Hudis, the ASCO CEO, shares ASCO's approach to the continued ABIM-MOC saga. With many oncologists expressing their angst about the MOC process, ASCO, under his leadership, approached the situation methodically, sending a survey to its members to quantify the problem and explore next steps. This is the FIRST time the results of this sur…