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BREAKING THROUGH with Madeline Bell


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BREAKING THROUGH with Madeline Bell
Children’s Hospital of Philadelphia
Madeline Bell, CEO of the renowned Children's Hospital of Philadelphia, takes you behind the scenes to meet the brilliant minds who are making - and supporting - incredible breakthroughs in pediatric medicine.
Want to hear two nerds talk about animals and what legends and superstitions humans have ascribed to them over the years? We're here for you.
latin Cover art photo provided by rawpixel on Unsplash: https://unsplash.com/@rawpixel
Series 1: 'A Life in Laughter' Maddy Smith, actor, comedian, writer and Bond Girl, discusses her career in her own words and 5 podcasts, with honesty, wit, charm, and laughter. In conversation with Bill Lawrance. Series 02: 'No Regrets' Maddy returns for 6 more episodes and more cafe conversations, taking deep dives to examine her career in children's TV, on location, in comedy, on the West End stage and most importantly how she has been guided by her instincts - without regrets. In conversa ...
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BREAKING THROUGH with Madeline Bell


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“Do What You Love”: Finding Medicines for Rare Diseases
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Hematologist and oncologist Denise Adams, MD, specializes in treating vascular anomalies, which occur when arteries, capillaries, veins or lymphatic vessels fail to develop correctly. She joins Madeline to discuss what the future holds for her field – and the surprising advice that inspired her to move forward in her career.…
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BREAKING THROUGH with Madeline Bell


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“I’ve Always Loved to Ask Why”: The Power of Mitochondrial Medicine
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Our mitochondria make the energy that keeps us alive. Geneticist Marni Falk, MD, joins Madeline to discuss what happens when our mitochondria don’t work properly, the breakthroughs she and her team are making for patients with mitochondrial disease, and the importance of having a strong vision for your career.…
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BREAKING THROUGH with Madeline Bell


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“There Was an Unmet Need”: Breakthroughs in Endocrinology
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While growing up in Panama, Diva DeLeón-Crutchlow, MD, MSCE, always wanted to understand how things worked. She speaks to Madeline about how her curiosity led her to pursue a career in medicine – and the work she’s doing today to develop new treatments for congenital hyperinsulinism and diabetes.بقلم Children’s Hospital of Philadelphia
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BREAKING THROUGH with Madeline Bell


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“We Have So Many Spine-Tingling Moments”: Treating Birth Defects Before Birth
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Pediatric and fetal surgeon Holly Hedrick, MD, has made life-changing breakthroughs for children with congenital diaphragmatic hernia and other rare birth defects. She joins Madeline to talk about the advice her mentors shared with her along the way – and the children who continue to inspire her every day.…
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“Research Is Our North Star”: The Future of Breakthroughs at CHOP
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In 2021, Susan Furth, MD, PhD, was named CHOP’s Chief Scientific Officer, becoming the first woman in CHOP’s 166-year history to hold this prestigious role. She joins Madeline to discuss CHOP’s trailblazing Frontier Programs, the importance of mentorship, and what the future holds for research at CHOP.…
In her first episode of Series 2, Maddy takes a deep dive into: a professional conflict, a difficult director and a cruel situation. And talks straight from the heart about wrong decisions, bad reviews, bad advice and typecasting. in conversation with Bill Lawrance
in her second episode of Series 2, Maddy takes a deep dive into: the West End theatre, Habeas Corpus, Alec Guinness, The Mousetrap, Donald Sinden - and the perils, pitfalls and pleasures of a long running stage play...
in her third episode of Series 2, Maddy takes a deep dive into: childhood acting and first professional comedy roles, studio audiences and canned laughter, funny men being serious - and her Masters of Comedy... in conversation with Bill Lawrance
In her fourth episode of Series 2 Maddy takes a deep dive into: mime and silent comedy, modern comedians, the decline of sitcom and the rise of stand-up, Steptoe & Son - and her favourite comedy roles... In conversation with Bill Lawrance
in this fifth episode of Series 2, Maddy takes a deep dive into: being on location, landlords and leading men, working with animals and bad weather, location catering, extras and stand ins - and the old BBC Television Centre... In conversation with Bill Lawrance
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The Madeline Smith podcasts


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SE02 ep06 'from children's TV to Mastermind'
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in her sixth episode of Series 2, Maddy takes a deep dive into: working in children's TV, the perils of onscreen nudity, learning lines and first night nerves - and appearing on TV celebrity quiz shows... in conversation with Bill Lawrance
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BREAKING THROUGH with Madeline Bell


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Sequenced: Using Genetics to Solve Medical Mysteries
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Strange symptoms with no clear cause. Medical histories that mystify even the most experienced doctors. Dr. Ian Krantz, Co-Director of CHOP’s Roberts Individualized Medical Genetics Center, specializes in solving “medical mysteries” – and he and his team have found answers for many patients who had almost given up hope. He joins Madeline to discuss…
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BREAKING THROUGH with Madeline Bell


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Transformed: Repairing Birth Defects Before Birth
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The idea of repairing birth defects before babies are born seemed like a radical one to many. But Dr. Scott Adzick, Director of CHOP’s Center for Fetal Diagnosis and Treatment, was determined to pursue it – and today, he’s considered a pioneer in the field of fetal surgery. He shares insights from his remarkable career with Madeline and reveals som…
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BREAKING THROUGH with Madeline Bell


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Realized: Delivering on the Promise of Gene Therapy
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World-renowned hematologist and scientist Dr. Katherine High has spent much of her career focused on achieving a goal few believed was possible: developing gene therapies and getting them to patients. Dr. High joins Madeline to talk about her journey from idea to breakthrough – and what it was like to create Spark Therapeutics, a company based on h…
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BREAKING THROUGH with Madeline Bell


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Inspired: Building a World-Class Hospital, Close to Home
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This fall, CHOP will celebrate an important milestone: the grand opening of its new hospital in King of Prussia, Pa. Dr. Jan Boswinkel, the Chief Operating Officer of the King of Prussia hospital, joins Madeline to talk about what this milestone means for patients, families and the community – and shares what it’s like to build a new hospital from …
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BREAKING THROUGH with Madeline Bell


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Discovered: Making Breakthroughs in Cardiac Care
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The team at CHOP’s Cardiac Center has been making life-changing breakthroughs for children for many years. The center’s co-director, pediatric heart surgeon Dr. Jonathan Chen, joins Madeline to discuss his team’s latest innovations – and to share his vision for the future of pediatric cardiac care.بقلم Children’s Hospital of Philadelphia
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BREAKING THROUGH with Madeline Bell


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Where We Are Now with Dr. Paul Offit: Vaccines
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How do the COVID-19 vaccines work? How concerned should we be about the new COVID-19 variants? Dr. Paul Offit, Director of CHOP’s Vaccine Education Center, is one of the leading voices in the vaccine conversation. On this special bonus episode, he joins Madeline to discuss the COVID-19 vaccines, the cutting-edge technology used to make them, and wh…
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The Madeline Smith podcasts


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SE01 ep1: 'A shop Girl in the Swinging 60s'
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In her first episode of series 1, Maddy walks out of the convent school gates for the last time, and steps into London's swinging sixties. Her wonderful adventures begin, with a job as a wide eyed shop assistant at the famous Biba boutique, in trendy Chelsea. In conversation with Bill Lawrance.
In her second episode of Series 1, Maddy adventures continue as, young and naive she begins her new career as a top model in Paris and across Europe. As the Sixties continue to swing, Maddy successfully navigating the pitfalls of an innocent abroad, then lands her first job as an actress in films. In conversation with Bill Lawrance.…
In her third episode of Series 1, Maddy makes her mark in a number of popular cult horror classics with the Hammer Film Studios, rising fast to becoming a favourite of directors, producers and audiences. Soon everyone wants Maddy, and a life in comedy beckons. In conversation with Bill Lawrance.
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The Madeline Smith podcasts


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SE01 ep04: 'Prime Time on the Telly'
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In her fourth episode of Series 1, Maddy becomes takes her first cue in London's TV studios. Quickly becoming a firm favourite with the nations top comedians and comic actors, as well as with prime time television audiences, Maddy is soon the darling of 1970s TV comedy, much loved and much in demand. In conversation with Bill Lawrance.…
In her fifth episode of Series 1, Maddy is chosen to be that iconic Bond Girl. Evermore in demand, Maddy finds her way onto the West End stage, and beyond, continuing her adventures with familiar faces from across the world of showbusiness. In conversation with Bill Lawrance.
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BREAKING THROUGH with Madeline Bell


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Where We Are Now with Dr. Susan Coffin: Transmission
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What makes COVID-19 different from other infectious diseases? Pediatric infectious disease specialist Dr. Susan Coffin, discusses her research on how the SARS-CoV-2 virus is transmitted, talks about how the virus affects children, and shares advice to help parents and families make decisions about everything from playdates to sports.…
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BREAKING THROUGH with Madeline Bell


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Where We Are Now with Dr. David Rubin: Modeling
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While many institutions across the country were modeling the trajectory of COVID-19 at the national level, Dr. David Rubin, and his colleagues at CHOP’s PolicyLab took a more innovative approach: They mapped the spread of the virus at the county level. More than 500 U.S. counties are included in the PolicyLab model, which has been used by local and…
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BREAKING THROUGH with Madeline Bell


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Where We Are Now with Dr. Rebecca Harris: Testing
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Testing is one of the most important tools we have to track and stop the spread of COVID-19, but it comes with many challenges. Dr. Rebecca Harris, Director of CHOP’s Infectious Disease Diagnostics Laboratory, shares the story of how CHOP developed its own COVID-19 test early in the pandemic and describes how her team is finding ways to do more tes…
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BREAKING THROUGH with Madeline Bell


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Where We Are Now with Dr. Audrey Odom John: Research
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Could dogs’ noses hold the answer to a better COVID-19 diagnostic test? Dr. Audrey Odom John, Chief of the Division of Pediatric Infectious Diseases at CHOP, discusses her efforts to develop a COVID-19 breathalyzer test with help from some four-legged friends – and shares the questions CHOP researchers most want to answer about the disease.…
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BREAKING THROUGH with Madeline Bell


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Where We Are Now with Dr. Edward Behrens: MIS-C
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In the spring, doctors began noticing a mysterious inflammatory condition in children that involved fever, rashes, diarrhea and vomiting. Now known as Multisystem Inflammatory Syndrome in Children, or MIS-C, the rare syndrome seems to be a postviral inflammatory response to COVID-19. Dr. Edward Behrens, Chief of the Division of Rheumatology and Dir…
In “Where We Are Now,” a five-episode special series, Madeline Bell speaks with five CHOP researchers about the COVID-19-related work they are leading – and about what gives them hope during this challenging time. With episodes focused on everything from a modeling tool that forecasts the spread of the virus across more than 500 U.S. counties to a …
Individuo-Sociedad
Lenguaje y pensamiento en la comunicación
Interacción social
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BREAKING THROUGH with Madeline Bell


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The Research and Lab of the Future with Dr. Beverly Davidson
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Join Madeline in CHOP’s “lab of the future” in the Leonard and Madlyn Abramson Pediatric Research Center. As Director of the Raymond G. Perelman Center for Cellular and Molecular Therapeutics and Chief Scientific Strategy Officer at CHOP, Dr. Davidson is developing innovative gene therapies to treat inherited brain disorders. Listen in as she talks…