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Join Tara Crawford-Parks, PhD, Director for Translational R&D and Product Enablement at DNA Genotek, to explore the potential of first void urine biomarkers in clinical diagnostics. Discover how this non-invasive sampling method is transforming HPV screening and opening new possibilities for early disease detection in oncology and infectious diseas…
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In this episode of the STEM Tea podcast, host AJ Hinton is joined by two science educators who are striving to instill a love of science and a sense of belonging within K–12 students through outreach initiatives and programs. Yelena Janumyan is a postdoctoral fellow at the Collaborative for STEM Education and Outreach at Vanderbilt University (TN, …
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In this podcast, Director of GLP bioanalysis Lan Li reviews immunoassays versus mass spectrometry-based methods as tools for protein biomarker quantitation. Focusing specifically on mass spectrometry approaches, Lan explores various methodologies, such as top-down, middle-down and bottom-up, as well as the sample preparation procedures required. La…
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In this episode of the STEM Tea podcast, AJ Hinton is joined by Ulises Ricoy, who was the Director of Outreach Initiatives at the University of Arizona (AZ, USA) at the time of this recording. Ulises has championed low-cost approaches to basic neuroscience research as well as educated underrepresented groups in STEM academia.In this episode, Ulises…
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In this episode of the STEM Tea podcast, host AJ Hinton is joined by Brielle Ferguson, Assistant Professor in Genetics and Neurology at Harvard (MA, USA), and Angeline J. Dukes, Assistant Professor in the Department of Neuroscience at the University of Minnesota (MN, USA). Brielle is a researcher studying the biomarkers of cognitive dysfunction and…
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In this episode of the STEM Tea podcast, host AJ Hinton is joined by Luis A. Leyva (left), Associate Professor of Mathematics Education & STEM Higher Education in the Peabody College of Education & Human Development at Vanderbilt University (TN, USA). Luis is the Director of the Power, Resistance & Identity in STEM Education (PRISM) Research Lab. H…
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In this episode of the STEM Tea podcast, host AJ Hinton is joined by Haysetta Shuler, an academic consultant in industrial–organizational psychology (I–O psychology) and a DEI mentor. Haysetta is an experienced administrator at a Historically Black College and University (HBCU), and she is passionate about increasing the involvement of Black studen…
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In this episode of the STEM Tea podcast, host AJ Hinton is joined by Corey Reynolds, a Regional Medical Scientific Director in industry. Corey’s background ranges from academics to industry consulting; he applies these varied experiences to mentoring the next generation of Black scientists.In this episode, Corey explains his current role as a medic…
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In this episode of the STEM Tea podcast, host AJ Hinton is joined by Clintoria Williams, Principal Investigator in the Kidney PathoPhysiology Research Group at Wright State University (OH, USA). Clintoria is a physiologist who is passionate about ‘lifting while climbing’ and is a co-founder of Black in Physiology. In this episode, Clintoria shares …
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In this episode of the STEM Tea podcast, AJ Hinton is joined by Alberto Vasquez, Academic Coordinator for the Center for Research in Educational Equity and Teaching (CREATE) at University of California, San Diego (CA, USA). Alberto is a biologist and educator, applying his lived experience to support students from underserved communities.At CREATE,…
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This International Women’s Day, we’re joined by Lindsay Davies, Chief Scientific Officer at NextCell Pharma (Stockholm, Sweden), to discuss the evolving role of cell therapies in treating autoimmune diseases.In this podcast, Davies breaks down the science behind NextCell’s mesenchymal stromal cell therapy for type 1 diabetes and explores how these …
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During the American Association of Pharmaceutical Scientists (AAPS) PharmSci 360 2024 conference, Bioanalysis Zone caught up with industry experts across numerous disciplines to discuss their involvement with AAPS and their research. In this interview, we spoke to Priyata Kalra about her talk on the use of GenAI within biomedicine.…
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In this episode, we sit down with Megan Cooley, Associate Director of Bioanalytical Services at ICON (KS, USA), to explore the cutting-edge world of antibody-drug conjugate (ADC) quantitation using high-resolution mass spectrometry (HRMS). Megan delves into the capabilities of Triple Quadrupole and Time-of-Flight mass spectrometry, offering her exp…
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In this interview, we discuss the potential of AI in increasing healthcare system efficiency, how medical devices are making procedures less invasive and what those working in the field of medical devices can do to help regulation catch up with innovation.بقلم Taylor & Francis Group
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In the sixth episode of The new frontier podcast, we're joined by Catherine Vrentas, Life Sciences Lead at Booz Allen Hamilton (VA, USA). Cathy explains how biomarkers can be used to predict the therapeutic outcome and efficacy of CGTs and the biomarkers in particular that have shown strong predictive value. We delve into the common challenges of w…
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We caught up with Principal Scientist Lindsay Denhoff (ICON; Dublin, Ireland) to discuss immunogenicity considerations for therapeutic proteins and the current analytical methodologies for detecting and characterizing anti-drug antibodies (ADAs). Lindsay shares some industry best practices for achieving high-quality ADA assays, as well as some of t…
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In this Tech Blast episode supported by Sartorius (Göttingen, Germany), we speak with David Apiyo – Manager of Applications Development at Sartorius (MN, USA) – about epitope binning, why it's performed and the best ways to conduct it. Plus, learn more about Sartorius' biolayer interferometry platforms and their application in epitope binning.…
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In this interview, we spoke to John Chappell, Senior Global Scientific Support Manager at Gyros Protein Technologies (Uppsala, Sweden) about his experience working with the Gyrolab platform for oligonucleotide assays. John discusses the advantages of using Gyrolab for oligo quantification in biological fluids and shares his thoughts on the next ste…
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In the fifth episode of The New Frontier podcast, we're joined by Paul Byrne, Senior Director of Genomics from ProtaGene (MA, USA). Paul describes his experience working with qPCR vs digital and digital droplet PCR assays and advises on their pros and cons, as well as when it's best to use each. We discuss how these assays can be optimized for cell…
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In this episode of The New Frontier podcast, we're joined by Daniel Schulz-Jander, Senior Director of Mass spectrometry Bioanalysis at QPS Netherlands (Groningen). Daniel explains how he uses immune-precipitation and immunoaffinity LC–MS techniques for his work relating to macromolecular pharmaceuticals like gene therapies, as well as their benefit…
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What disparities exist in cancer screening and how does this impact patient outcomes? Listen to our latest podcast episode with Kilan Ashad-Bishop (American Cancer Society) to find out about the intersection between science, health, and society.بقلم Taylor & Francis Group
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In this episode, we spoke to Senior Director Johanna Mora about her experience with immunogenicity testing for cell and gene therapies (CGTs) and how she prepared for the expansion of BMS's portfolio to include CGTs. We discuss the importance of having diverse teams with a broad range of experiences to solve complex problems, as well as the role of…
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In the first episode of this series, we spoke to Executive Director and Global Head of Regulatory Services Kimberley Buytaert-Hoefen about her experience with cell and gene therapy (CGT) approvals and the barriers to getting these important therapeutics to the patient. Kim advises early regulatory interaction and collaboration to improve the succes…
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In our new podcast series, we're joined by a Bioanalysis author to review their publication's biggest challenges, wider implications and next steps. In the final episode of series one, we're joined by Hetal Sarvaiya and Yuting Wang from AbbVie (MA, USA), who talk about the challenges of having an international team working on their perspective arti…
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In this Tech Blast episode supported by Sartorius, we speak with Derrick Christopher Campos, Product Manager at Sartorius (TX, USA), about Surface Plasmon Resonance (SPR). This tried-and-true technique allows researchers to do label-free protein characterization; in this podcast, Derrick discusses how Sartorius improves upon multi-cycle kinetics wi…
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In our new podcast series, we're joined by a Bioanalysis author to review their publication's biggest challenges, wider implications and next steps. In episode four, we're joined by Senior Scientist and Technical Specialist Ashley Phillips. Ashley's publication assessed the performance of next-generation trypsins for rapid protein LC-MS bioanalysis…
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In our new podcast series, we're joined by a Bioanalysis author to review their publication's biggest challenges, wider implications and next steps. In episode three, Digital Editor Ellen Williams is joined by Clinical Instructor and Education Coordinator Camilla Linder and Biomedical Laboratory Scientist Miguel Gambell Barroso. The collaborative p…
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In this episode of Talking Techniques, Ritwika Biswas, Field Scientist at Sino Biological US Inc. (PA, USA), walks us through the chimeric antigen receptor (CAR) development process and how T and natural killer (NK) cells can be utilized to carry these modular synthetic molecules. Ritwika also addresses the safety and efficacy of these cell therapi…
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In this Tech Blast episode, we explore preparing 3D cell cultures with Sartorius’ (Goettingen, Germany) Sandra Söderholm, Application Development Specialist, and Maria Voutilainen, Product Manager. Sandra and Maria give us an introduction to 3D cell cultures and how to prepare them, and then delve into a foundational technique that is often overloo…
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In our new podcast series, we're joined by a Bioanalysis author to review their publication's biggest challenges, wider implications and next steps. In episode two, Ellen is joined by Research Assistant Gaudry Troché to discuss conventional sampling and microsampling for the comparison of pharmacokinetic study profiles of insulin. Gaudry discusses …
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In this episode of Talking Techniques, Ritwika Biswas, Field Scientist at Sino Biological US Inc., walks us through the chimeric antigen receptor (CAR) development process and how T and natural killer (NK) cells can be utilized to carry these modular synthetic molecules. Ritwika also addresses the safety and efficacy of these cell therapies as well…
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In this episode, supported by Fortis Life Sciences, we delve into the relationship between mitochondria, inflammation and cancer, discussing the new techniques that are bearing fruit in this field, such as spatial analysis.Our expert insight for this episode comes from Phillip West, Principle Investigator of the West lab at Texas A&M Medicine (TX, …
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